TOMM22 - translocase of outer mitochondrial membrane 22 Gene

Homo sapiens

Also known as 1C9-2; TOM22; MST065; MSTP065

Gene ID: 56993 | Gene type: protein coding

About TOMM22

Cytogenetic location: 22q13.1 Genomic coordinates (GRCh38): 22:38,681,957-38,685,421 (from NCBI)

This gene has 2 transcripts (splice variants) and 213 orthologues. Ubiquitous expression in colon (RPKM 24.2), kidney (RPKM 23.3) and 25 other tissues.

Summary

The protein encoded by this gene is an integral membrane protein of the mitochondrial outer membrane. The encoded protein interacts with TOMM20 and TOMM40, and forms a complex with several Other proteins to import cytosolic preproteins into the mitochondrion. [provided by RefSeq, Jul 2008]

TOMM22 Products(1)

mRNA	Protein	Name
NM_020243.5	NP_064628.1	mitochondrial import receptor subunit TOM22 homolog

TOMM22 Protein Structure

Tom22

0
100
142 a.a.

Protein Preferred Names

Protein Names

mitochondrial import receptor subunit TOM22 homolog

mitochondrial import receptor Tom22

TOMM22 Protein-protein interaction Information

Type Cross Intra	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Reference
Intra	TOMM22	Q9NS69	TOMM7	Homo sapiens	Q9P0U1	BN-PAGE	12198123
Intra	TOMM22	Q9NS69	AQP6	Homo sapiens	Q13520	Y2H Array	32296183
Intra	TOMM22	Q9NS69	AQP6	Homo sapiens	Q13520	Y2H Prey Pooling	32296183

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases

Alias

3-Methylglutaconic Aciduria, Type V

3-Methylglutaconic Aciduria Type 5	Mga5
MGCA5	Dcma
Dcma Syndrome	Dilated Cardiomyopathy With Ataxia
3-Methylglutaconic Aciduria Type V	Mga Type V
Cardiomyopathy, Dilated, With Ataxia	Mga, Type V
Dilated Cardiomyopathy With Ataxia Syndrome	Dnajc19 Defect
3-Methylglutaconic Aciduria 5	3-Alpha-Methylglutaconic Aciduria Type 5
3-@Methylglutaconic Aciduria, Type V

3-Methylglutaconic Aciduria, Type Iii

Optic Atrophy	3-Methylglutaconic Aciduria Type 3
Costeff Syndrome	Mga3
Costeff Optic Atrophy Syndrome	Optic Atrophy Plus Syndrome
Infantile Optic Atrophy With Chorea And Spastic Paraplegia	3-Methylglutaconic Aciduria Type Iii
Autosomal Recessive Optic Atrophy Plus Syndrome	Autosomal Recessive Optic Atrophy Type 3
Opa3 Defect	MGCA3
Mga, Type Iii	Iraqi Jewish Optic Atrophy Plus
Mga Type Iii	Optic Atrophy, Infantile, With Chorea And Spastic Paraplegia
Iraqi-Jewish 'Optic Atrophy Plus'	Optic Atrophy 3, Autosomal Recessive
Opa3, Autosomal Recessive	Opa3-Related 3-Methylglutaconic Aciduria
Iraqi-Jewish Optic Atrophy Plus	Atrophy Of Optic Disc
3-Alpha Methylglutaconic Aciduria Type Iii	Optic Atrophy 3
Optic Atrophy Infantile With Chorea And Spastic Paraplegia	Autosomal Recessive Opa3
Autosomal Recessive Optic Atrophy 3	3-Methylglutaconic Aciduria 3
3-Alpha-Methylglutaconic Aciduria Type 3	Optic Atrophy 3 Autosomal Recessive
Atrophy, Optic	Atrophy, Optic, Plus Syndrome
Optic Nerve Atrophy	Primary Optic Atrophy
Oa - [Optic Atrophy]	Second Cranial Nerve Atrophy
Second Cranium Nerve Atrophy

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS14880	TOMM22 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Bos taurus	TOMM22	VGNC	VGNC:49064
Felis catus	TOMM22	VGNC	VGNC:66443
Macaca mulatta	TOMM22	VGNC	VGNC:98461
Mus musculus	TOMM22	MGD	MGI:2450248
Rattus norvegicus	TOMM22	RGD	RGD:1303260

Name
Email *

	Sorry, but the email address you supplied was invalid.