CAMK1D - calcium/calmodulin dependent protein kinase ID Gene

Homo sapiens

Also known as CKLiK; CaM-K1; CaMKID

Gene ID: 57118 | Gene type: protein coding

About CAMK1D

Cytogenetic location: 10p13 Genomic coordinates (GRCh38): 10:12,349,547-12,835,545 (from NCBI)

This gene has 3 transcripts (splice variants), 267 orthologues and 22 paralogues. Broad expression in brain (RPKM 10.9), skin (RPKM 4.6) and 21 other tissues.

Summary

This gene is a member of the calcium/calmodulin-dependent protein kinase 1 family, a subfamily of the serine/threonine kinases. The encoded protein is a component of the calcium-regulated calmodulin-dependent protein kinase cascade. It has been associated with multiple processes including regulation of granulocyte function, activation of CREB-dependent gene transcription, aldosterone synthesis, differentiation and activation of neutrophil cells, and Apoptosis of erythroleukemia cells. Alternatively spliced transcript variants encoding different isoforms of this gene have been described. [provided by RefSeq, Jan 2015]

CAMK1D Products(3)

mRNA	Protein	Name
NM_001351032.2	NP_001337961.1	calcium/calmodulin-dependent protein kinase type 1D isoform 3
NM_020397.4	NP_065130.1	calcium/calmodulin-dependent protein kinase type 1D isoform 1
NM_153498.4	NP_705718.1	calcium/calmodulin-dependent protein kinase type 1D isoform 2

CAMK1D Protein Structure

Pkinase

0
100
200
300
385 a.a.

Protein Preferred Names

Protein Names

calcium/calmodulin-dependent protein kinase type 1D

CAMK1D/ANAPC5 fusion

Recombinant CAMK1D Proteins

Cat. No.	Product Name	Accession	Purity
HY-P7715	CAMKI delta/CAMK1D Protein, Human (GST)	Q8IU85-1 (M1-K385)	≥95%

Related Diseases

Diseases

Alias

Ceroid Lipofuscinosis, Neuronal, 6a

Neuronal Ceroid Lipofuscinosis 6	CLN6
Vlincl	Cln6 Disease
Ceroid Lipofuscinosis, Neuronal, 6	Late-Infantile Neuronal Ceroid Lipofuscinosis
CLN6A	Neuronal Ceroid Lipofuscinosis, Late Infantile, Variant
Neuronal Ceroid Lipofuscinosis 6a	Neuronal Ceroid Lipofuscinosis 6 Variable Age Of Onset
Cln6 Disease, Adult Kufs Type A	Cln6 Disease, Late Infantile
Neuronal Ceroid Lipofuscinosis, Gypsy/Indian Early Juvenile Variant	Ceroid Lipofuscinosis Neuronal 6
Cln6-Related Neuronal Ceroid Lipofuscinosis	Late Infantile Neuronal Ceroid Lipofuscinosis
Jansky-Bielschowsky Disease	Lincl
Late Infantile Ncl	Neuronal Ceroid Lipofuscinosis 6 With Variable Age At Onset
Variant Late-Onset Infantile Neuronal Ceroid Lipofuscinosis	Ceroid Lipofuscinosis, Neuronal, Late Infantile, Variant
Lipofuscinosis, Ceroid, Neuronal, Type 6	Ceroid Lipofuscinosis, Neuronal, 5

Wolfram Syndrome 1

WFS1	Didmoad
Wfs	Diabetes Mellitus And Insipidus With Optic Atrophy And Deafness
Diabetes Insipidus And Mellitus With Optic Atrophy And Deafness	Diabetes Insipidus And Mellitus With Optic Atrophy And Deafness Syndrome
Wolfram Syndrome

Type 2 Diabetes Mellitus

Insulin Resistance	NIDDM
Type 2 Diabetes	Diabetes Mellitus, Non-Insulin-Dependent
T2D	Noninsulin-Dependent Diabetes Mellitus
Diabetes Mellitus, Type Ii	Maturity-Onset Diabetes
Insulin Resistance, Severe, Digenic	Diabetes Mellitus, Type 2
Diabetes Mellitus, Noninsulin-Dependent	Diabetes Mellitus, Noninsulin-Dependent, Association With
Diabetes Mellitus, Noninsulin-Dependent, Late Onset	Hypertension, Insulin Resistance-Related, Susceptibility To
Insulin Resistance, Susceptibility To	Non-Insulin-Dependent Diabetes Mellitus
Type Ii Diabetes Mellitus	Adult-Onset Diabetes Mellitus
Maturity-Onset Diabetes Mellitus	Diabetes Mellitus Type 2
Type Ii Diabetes	Type 2 Diabetes Mellitus, Susceptibility To
Diabetes, Type 2	Diabetes Mellitus, Noninsulin-Dependent, Susceptibility To
Diabetes Mellitus, Non-Insulin-Dependent, Susceptibility To	Diabetes Mellitus, Type 2, Susceptibility To
Diabetes Mellitus, Noninsulin-Dependent, 2	Diabetes Mellitus, Type Ii, Susceptibility To
Hypertension, Insulin Resistance-Related	Adult-Onset Diabetes
Aodm	Diabetes Mellitus, Adult-Onset
Diabetes Mellitus Type Ii	Diabetes Mellitus Type 2, Susceptibility To
Diabetes, Type Ii, Susceptibility To	Diabetes Type 2
Diabetes Mellitus	Adult Onset Diabetes
Maturity Onset Diabetes	Nonketotic Diabetes
Non-Insulin Dependent Diabetes Mellitus	T2dm - [Type 2 Diabetes Mellitus]
Niddm - [Non Insulin Dependent Diabetes Mellitus]	Dm2
Dm Type Ii	Diabetic Type 2
Insulin Requiring Type 2 Diabetes	Noninsulin Dependent Diabetes
Non-Insulin-Dependent Diabetes Mellitus Without Complications	Diabetes Due To Insulin Secretory Defect
Diabetes Mellitus Due To Insulin Secretory Defect	Non-Insulin-Dependent Diabetes Of The Young
Senile Diabetes	Nonketotic Hyperglycaemia
Stable Diabetes

Diabetes Mellitus

Diabetes

Maturity-Onset Diabetes Of The Young

MODY	Maturity Onset Diabetes Mellitus In Young
Mason-Type Diabetes	Mason Type Diabetes
Maturity Onset Diabetes Of The Young	Mody Syndrome
Diabetes Of The Young, Maturity-Onset

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (4)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-148913	CS587	Inhibitor	98.11%	Unkown
HY-148907	CS640	Inhibitor	99.43%	Unkown
HY-156871	CAMK1D-IN-1		/	Unkown
HY-RS01852	CAMK1D Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Mus musculus	CAMK1D	MGD	MGI:2442190
Bos taurus	CAMK1D	VGNC	VGNC:58595
Macaca mulatta	CAMK1D	VGNC	VGNC:70579
Rattus norvegicus	CAMK1D	RGD	RGD:1560691
Canis familiaris	CAMK1D	VGNC	VGNC:38678
Felis catus	CAMK1D	VGNC	VGNC:60329
Others	CAMK1D	NCBI

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