TRAPPC1 - trafficking protein particle complex subunit 1 Gene

Homo sapiens

Also known as BET5; MUM2

Gene ID: 58485 | Gene type: protein coding

About TRAPPC1

Cytogenetic location: 17p13.1 Genomic coordinates (GRCh38): 17:7,930,345-7,931,999 (from NCBI)

This gene has 7 transcripts (splice variants), 183 orthologues and 1 paralogue. Ubiquitous expression in placenta (RPKM 52.2), lymph node (RPKM 50.3) and 25 other tissues.

Summary

This gene product plays a role in vesicular transport of proteins to the Golgi apparatus from the endoplasmic reticulum. The encoded protein is a component of the multisubunit transport protein particle (TRAPP) complex. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Oct 2009]

TRAPPC1 Products(2)

mRNA	Protein	Name
NM_001166621.1	NP_001160093.1	trafficking protein particle complex subunit 1
NM_021210.5	NP_067033.1	trafficking protein particle complex subunit 1

Gene Ontology

Molecular Function

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	28514442	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

TRAPPC1 Protein Structure

Sybindin

0
100
145 a.a.

Protein Preferred Names

Protein Names

trafficking protein particle complex subunit 1

BET5 homolog

Related Diseases

Diseases

Alias

Spondyloepiphyseal Dysplasia Tarda, X-Linked

Spondyloepiphyseal Dysplasia Tarda	X-Linked Spondyloepiphyseal Dysplasia Tarda
SEDT	Sed Tarda, X-Linked
Spondyloepiphyseal Dysplasia, Late	Spondyloepiphyseal Dysplasia Tarda X-Linked
Sed	X Linked Spondyloepiphyseal Dysplasia Tarda
X-Linked Spondyloepiphyseal Dysplasia	Late Onset Spondyloepiphyseal Dysplasia
Sed Tarda	X-Linked Sed
X-Linked Sedt	Dysplasia, Spondyloepiphyseal, Tarda
Spondyloepiphyseal Dysplasia

Melanoma

Malignant Melanoma	Cutaneous Melanoma
Naevocarcinoma	Malignant Melanomas

Autosomal Recessive Intellectual Developmental Disorder

Mental Retardation, Autosomal Recessive	Autosomal Recessive Mental Retardation
Autosomal Recessive Non-Syndromic Mental Retardation	Autosomal Recessive Non-Syndromic Intellectual Disability

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS14985	TRAPPC1 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Bos taurus	TRAPPC1	VGNC	VGNC:36284
Mus musculus	TRAPPC1	MGD	MGI:1098727
Canis familiaris	TRAPPC1	VGNC	VGNC:47777
Macaca mulatta	TRAPPC1	VGNC	VGNC:79208
Felis catus	TRAPPC1	VGNC	VGNC:66508
Rattus norvegicus	TRAPPC1	RGD	RGD:1311365

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