1. Gene
  2. TRAPPC3 - trafficking protein particle complex subunit 3 Gene

TRAPPC3 - trafficking protein particle complex subunit 3 Gene

Homo sapiens

Also known as BET3

Gene ID: 27095 | Gene type: protein coding

About TRAPPC3

Cytogenetic location: 1p34.3 Genomic coordinates (GRCh38): 1:36,136,572-36,156,053 (from NCBI)

This gene has 10 transcripts (splice variants), 213 orthologues and 1 paralogue. Ubiquitous expression in thyroid (RPKM 23.9), adrenal (RPKM 19.7) and 25 other tissues.

Summary

This gene encodes a component of the trafficking protein particle complex, which tethers transport vesicles to the cis-Golgi membrane. The encoded protein participates in the regulation of transport from the endoplasmic reticulum to the Golgi apparatus. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012]

TRAPPC3 Products(5)

mRNA Protein Name
NM_001270894.2 NP_001257823.1 trafficking protein particle complex subunit 3 isoform 2
NM_001270895.2 NP_001257824.1 trafficking protein particle complex subunit 3 isoform 3
NM_001270896.2 NP_001257825.1 trafficking protein particle complex subunit 3 isoform 3
NM_001270897.2 NP_001257826.1 trafficking protein particle complex subunit 3 isoform 4
NM_014408.5 NP_055223.1 trafficking protein particle complex subunit 3 isoform 1
Gene Ontology
  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
16189514 GOA
Cellular Component GO Annotation Evidence Reference Source
part of TRAPP complex IDA
IDA: Inferred from direct assay
21525244 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

TRAPPC3 Protein Structure

TRAPP

TRAPP: Transport protein particle (TRAPP) component (18 - 166)

  • 0
  • 100
  • 180 a.a.
Protein Preferred Names Protein Names

trafficking protein particle complex subunit 3

trafficking protein particle complex 3

Related Diseases

Diseases Alias
Spondyloepiphyseal Dysplasia Tarda, X-Linked

Spondyloepiphyseal Dysplasia Tarda

X-Linked Spondyloepiphyseal Dysplasia Tarda

SEDT

Sed Tarda, X-Linked

Spondyloepiphyseal Dysplasia, Late

Spondyloepiphyseal Dysplasia Tarda X-Linked

Sed

X Linked Spondyloepiphyseal Dysplasia Tarda

X-Linked Spondyloepiphyseal Dysplasia

Late Onset Spondyloepiphyseal Dysplasia

Sed Tarda

X-Linked Sed

X-Linked Sedt

Dysplasia, Spondyloepiphyseal, Tarda

Spondyloepiphyseal Dysplasia

Bardet-Biedl Syndrome

Bbs

Biedl-Bardet Syndrome

Celery Allergy
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Orthologs Information

Species Symbol Source ID
Rattus norvegicus TRAPPC3 RGD RGD:1309135
Mus musculus TRAPPC3 MGD MGI:1351486
Felis catus TRAPPC3 VGNC VGNC:107683
Canis familiaris TRAPPC3 VGNC VGNC:47781
Macaca mulatta TRAPPC3 VGNC VGNC:79210
Bos taurus TRAPPC3 VGNC VGNC:36288