2. Gene
  3. SLC28A3 - solute carrier family 28 member 3 Gene

SLC28A3 - solute carrier family 28 member 3 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens

Also known as CNT3

Gene ID: 64078 | Gene type: protein coding

About SLC28A3

Cytogenetic location: 9q21.32-q21.33 Genomic coordinates (GRCh38): 9:84,275,457-84,368,727 (from NCBI)

This gene has 2 transcripts (splice variants), 196 orthologues and 2 paralogues. Biased expression in gall bladder (RPKM 4.2), bone marrow (RPKM 3.2) and 11 other tissues.

Summary

Nucleoside transporters, such as SLC28A3, regulate multiple cellular processes, including neurotransmission, vascular tone, adenosine concentration in the vicinity of cell surface receptors, and transport and metabolism of nucleoside drugs. SLC28A3 shows broad specificity for pyrimidine and purine nucleosides (Ritzel et al., 2001 [PubMed 11032837]).[supplied by OMIM, Mar 2008]

SLC28A3 Products(2)

mRNA Protein Name
NM_001199633.2 NP_001186562.1 solute carrier family 28 member 3
NM_022127.3 NP_071410.1 solute carrier family 28 member 3

SLC28A3 Protein Structure

Nucleos_tra2_N

Nucleos_tra2_N: Na+ dependent nucleoside transporter N-terminus (206 - 277)

Gate

Gate: Nucleoside recognition (286 - 381)

Nucleos_tra2_C

Nucleos_tra2_C: Na+ dependent nucleoside transporter C-terminus (388 - 612)

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  • 691 a.a.
Protein Preferred Names Protein Names

solute carrier family 28 member 3

concentrative Na(+)-nucleoside cotransporter 3

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS13152 SLC28A3 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus SLC28A3 RGD RGD:621224
Macaca mulatta SLC28A3 VGNC VGNC:77493
Bos taurus SLC28A3 VGNC VGNC:34793
Mus musculus SLC28A3 MGD MGI:2137361
Felis catus SLC28A3 VGNC VGNC:65295