2. Gene
  3. ETNPPL - ethanolamine-phosphate phospho-lyase Gene

ETNPPL - ethanolamine-phosphate phospho-lyase Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as AGXT2L1

Gene ID: 64850 | Gene type: protein coding

About ETNPPL

Cytogenetic location: 4q25 Genomic coordinates (GRCh38): 4:108,742,053-108,763,053 (from NCBI)

This gene has 10 transcripts (splice variants), 195 orthologues and 4 paralogues. Biased expression in liver (RPKM 37.5), brain (RPKM 36.7) and 3 other tissues.

Summary

Enables ethanolamine-phosphate phospho-lyase activity. Predicted to be located in mitochondrial matrix. [provided by Alliance of Genome Resources, Apr 2022]

ETNPPL Products(6)

mRNA Protein Name
NM_001146590.2 NP_001140062.1 ethanolamine-phosphate phospho-lyase isoform 2
NM_001146627.2 NP_001140099.1 ethanolamine-phosphate phospho-lyase isoform 3
NM_001331031.2 NP_001317960.1 ethanolamine-phosphate phospho-lyase isoform 4
NM_001331032.2 NP_001317961.1 ethanolamine-phosphate phospho-lyase isoform 4
NM_001331033.2 NP_001317962.1 ethanolamine-phosphate phospho-lyase isoform 5
NM_031279.4 NP_112569.2 ethanolamine-phosphate phospho-lyase isoform 1
Gene Ontology
  • Molecular Function
Molecular Function GO Annotation Evidence Reference Source
enables ethanolamine-phosphate phospho-lyase activity IDA
IDA: Inferred from direct assay
22241472 GOA
enables protein binding IPI
IPI: Inferred from physical interaction
28514442 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

ETNPPL Protein Structure

Aminotran_3

Aminotran_3: Aminotransferase class-III (33 - 373)

  • 0
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  • 400
  • 499 a.a.
Protein Preferred Names Protein Names

ethanolamine-phosphate phospho-lyase

alanine--glyoxylate aminotransferase 2-like 1

Related Diseases

Diseases Alias
Alcohol Dependence

Alcoholism

Alcohol Dependence, Susceptibility To

Alcohol Dependence, Protection Against

Aerodigestive Tract Cancer, Squamous Cell, Alcohol-Related, Protection Against

Alcoholism, Susceptibility To

Alcoholic Intoxication, Chronic

Pharyngeal Neoplasms

Chronic Alcoholism

Dipsomania

Alcohol Addiction

Ethanol Dependence

Chronic Ethanolism

Chronic Alcoholic Disease Nos

Alcoholic Disease Nos

Alcoholic
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS04561 ETNPPL Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus ETNPPL VGNC VGNC:53712
Canis familiaris ETNPPL VGNC VGNC:97193
Rattus norvegicus ETNPPL RGD RGD:1590098
Mus musculus ETNPPL MGD MGI:1919010
Felis catus ETNPPL VGNC VGNC:78488
Macaca mulatta ETNPPL VGNC VGNC:81399