AIDA - axin interactor, dorsalization associated Gene

Homo sapiens

Also known as C1orf80

Gene ID: 64853 | Gene type: protein coding

About AIDA

Cytogenetic location: 1q41 Genomic coordinates (GRCh38): 1:222,668,013-222,712,491 (from NCBI)

This gene has 6 transcripts (splice variants) and 203 orthologues. Ubiquitous expression in fat (RPKM 42.6), testis (RPKM 31.5) and 25 other tissues.

Summary

Predicted to enable phosphatidylinositol binding activity. Acts upstream of or within negative regulation of JUN kinase activity. Predicted to be located in cytoplasm. Predicted to be active in membrane. [provided by Alliance of Genome Resources, Apr 2022]

AIDA Products(1)

mRNA	Protein	Name
NM_022831.4	NP_073742.2	axin interactor, dorsalization-associated protein

Gene Ontology

Molecular Function
Biological Process

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	21900206	GOA

Biological Process GO Annotation	Evidence	Reference	Source
acts upstream of or within negative regulation of JUN kinase activity	IDA IDA: Inferred from direct assay	17681137	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

AIDA Protein Structure

Aida_N

Aida_C2

0
100
200
306 a.a.

Protein Preferred Names

Protein Names

axin interactor, dorsalization-associated protein

axin interaction partner and dorsalization antagonist

AIDA Protein-protein interaction Information

Type Cross Intra	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Reference
Intra	AIDA	Q96BJ3	DDX41	Homo sapiens	Q9UJV9	Validated Y2H	32296183
Intra	AIDA	Q96BJ3	DDX41	Homo sapiens	Q9UJV9	Y2H Array	32296183
Intra	AIDA	Q96BJ3	DDX41	Homo sapiens	Q9UJV9	Y2H Prey Pooling	32296183
Intra	AIDA	Q96BJ3	RPL36A	Homo sapiens	P83881	Y2H Prey Pooling	32296183
Intra	AIDA	Q96BJ3	RPL36A	Homo sapiens	P83881	Y2H Array	32296183
Intra	AIDA	Q96BJ3	EMSY	Homo sapiens	Q7Z589-5	Y2H Array	32296183
Intra	AIDA	Q96BJ3	EMSY	Homo sapiens	Q7Z589-5	Y2H Prey Pooling	32296183
Intra	AIDA	Q96BJ3	PINX1	Homo sapiens	Q96BK5	Y2H Prey Pooling	32296183
Intra	AIDA	Q96BJ3	PINX1	Homo sapiens	Q96BK5	Validated Y2H	32296183
Intra	AIDA	Q96BJ3	PINX1	Homo sapiens	Q96BK5	Y2H Array	32296183
Intra	AIDA	Q96BJ3	PINX1	Homo sapiens	Q96BK5	Y2H	21900206
Intra	AIDA	Q96BJ3	LNX1	Homo sapiens	Q8TBB1	Y2H Prey Pooling	25416956
Intra	AIDA	Q96BJ3	LNX1	Homo sapiens	Q8TBB1	Validated Y2H	25416956
Intra	AIDA	Q96BJ3	DDIT4L	Homo sapiens	Q96D03	Y2H Prey Pooling	32296183
Intra	AIDA	Q96BJ3	DDIT4L	Homo sapiens	Q96D03	Validated Y2H	32296183
Intra	AIDA	Q96BJ3	DDIT4L	Homo sapiens	Q96D03	Y2H Array	32296183
Intra	AIDA	Q96BJ3	FAM118A	Homo sapiens	Q9NWS6	Y2H Array	32296183
Intra	AIDA	Q96BJ3	FAM118A	Homo sapiens	Q9NWS6	Y2H Prey Pooling	32296183
Intra	AIDA	Q96BJ3	FAM118A	Homo sapiens	Q9NWS6	Y2H Prey Pooling	25416956
Intra	AIDA	Q96BJ3	FAM118A	Homo sapiens	Q9NWS6	Validated Y2H	32296183

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

Clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Phase
HY-101311	UPF-523	Antagonist	99.89%	Phase 4

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS00489	AIDA Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Mus musculus	AIDA	MGD	MGI:1919737
Macaca mulatta	AIDA	VGNC	VGNC:99840
Canis familiaris	AIDA	VGNC	VGNC:37734
Rattus norvegicus	AIDA	RGD	RGD:1592746
Bos taurus	AIDA	VGNC	VGNC:25758
Felis catus	AIDA	VGNC	VGNC:59699

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