Clip1 - CAP-GLY domain containing linker protein 1 Gene

Rattus norvegicus

Also known as Rsn; CLIP-170

Gene ID: 65201 | Gene type: protein coding

About Clip1

Summary

Enables microtubule plus-end binding activity. Involved in positive regulation of dendrite development. Located in cytoplasmic microtubule and microtubule plus-end. Orthologous to human CLIP1 (CAP-Gly domain containing linker protein 1). [provided by Alliance of Genome Resources, Apr 2022]

Clip1 Products(4)

mRNA	Protein	Name
NM_001408966.1	NP_001395895.1	CAP-Gly domain-containing linker protein 1 isoform 2
NM_031745.3	NP_113933.2	CAP-Gly domain-containing linker protein 1 isoform 1
NM_001408966.1	NP_001395895.1	CAP-Gly domain-containing linker protein 1 isoform 2
NM_031745.3	NP_113933.2	CAP-Gly domain-containing linker protein 1 isoform 1

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables microtubule binding	IDA IDA: Inferred from direct assay	26972003	RGD
enables microtubule plus-end binding	IDA IDA: Inferred from direct assay	11290329	RGD
enables protein binding	IPI IPI: Inferred from physical interaction	11290329	RGD

Biological Process GO Annotation	Evidence	Reference	Source
involved in positive regulation of dendrite development	IMP IMP: Inferred from mutant phenotype	21430156	RGD

Cellular Component GO Annotation	Evidence	Reference	Source
located in cytoplasmic microtubule	IDA IDA: Inferred from direct assay	11290329	RGD
located in microtubule plus-end	IDA IDA: Inferred from direct assay	26972003	RGD

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

CAP-Gly domain-containing linker protein 1

cytoplasmic linker protein 170	restin (Reed-Steinberg cell-espressed intermediate filament-associated protein)
restin (Reed-Steinberg cell-expressed intermediate filament-associated protein)

Clip1 Protein-protein interaction Information

Type Cross Intra	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Reference
Cross	Clip1	Q9JK25	CSNK2B	Homo sapiens	P67870	Anti Bait CoIP	20664522
Cross	Clip1	Q9JK25	CLASP1	Homo sapiens	Q7Z460	BiFC	11290329

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS02810	CLIP1 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Clip1	NCBI	NCBI:6249

Name
Email *

	Sorry, but the email address you supplied was invalid.