SNAPC1 - small nuclear RNA activating complex polypeptide 1 Gene

Homo sapiens

Also known as SNAP43; PTFgamma

Gene ID: 6617 | Gene type: protein coding

About SNAPC1

Cytogenetic location: 14q23.2 Genomic coordinates (GRCh38): 14:61,762,420-61,796,428 (from NCBI)

This gene has 1 transcript (splice variant) and 252 orthologues. Broad expression in testis (RPKM 12.5), adrenal (RPKM 5.0) and 24 other tissues.

Summary

Predicted to enable sequence-specific DNA binding activity. Predicted to be involved in snRNA transcription by RNA polymerase II and snRNA transcription by RNA polymerase III. Located in nucleolus and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]

SNAPC1 Products(1)

mRNA	Protein	Name
NM_003082.4	NP_003073.1	snRNA-activating protein complex subunit 1

Gene Ontology

Molecular Function

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	11056176	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

SNAPC1 Protein Structure

SNAPc_SNAP43

0
100
200
300
368 a.a.

Protein Preferred Names

Protein Names

snRNA-activating protein complex subunit 1

PSE-binding factor subunit gamma

SNAPC1 Protein-protein interaction Information

Type Cross Intra	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Reference
Intra	SNAPC1	Q16533	SNAPC3	Homo sapiens	Q92966	Anti Bait CoIP	11056176
Intra	SNAPC1	Q16533	SNAPC3	Homo sapiens	Q92966	GMS	36369505
Intra	SNAPC1	Q16533	SNAPC3	Homo sapiens	Q92966	Anti Tag CoIP	33961781
Intra	SNAPC1	Q16533	SNAPC3	Homo sapiens	Q92966	Anti Tag CoIP	28514442
Intra	SNAPC1	Q16533	SNAPC3	Homo sapiens	Q92966	Validated Y2H	32296183
Intra	SNAPC1	Q16533	SNAPC4	Homo sapiens	Q5SXM2	Anti Tag CoIP	33961781
Intra	SNAPC1	Q16533	SNAPC4	Homo sapiens	Q5SXM2	Anti Tag CoIP	28514442
Intra	SNAPC1	Q16533	SNAPC4	Homo sapiens	Q5SXM2	Anti Bait CoIP	11056176
Intra	SNAPC1	Q16533	SNAPC4	Homo sapiens	Q5SXM2	GMS	36369505
Intra	SNAPC1	Q16533	EXOC8	Homo sapiens	Q8IYI6	Validated Y2H	32296183

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS13478	SNAPC1 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Macaca mulatta	SNAPC1	VGNC	VGNC:77665
Mus musculus	SNAPC1	MGD	MGI:1922877
Rattus norvegicus	SNAPC1	RGD	RGD:1304671
Felis catus	SNAPC1	VGNC	VGNC:65519
Bos taurus	SNAPC1	VGNC	VGNC:35054
Canis familiaris	SNAPC1	VGNC	VGNC:46591

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