2. Gene
  3. Lrg1 - leucine-rich alpha-2-glycoprotein 1 Gene

Lrg1 - leucine-rich alpha-2-glycoprotein 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Lrg; Lrhg; 1300008B03Rik; 2310031E04Rik

Gene ID: 76905 | Gene type: protein coding

About Lrg1

Summary

Enables transforming growth factor beta receptor binding activity. Acts upstream of or within several processes, including brown fat cell differentiation; positive regulation of endothelial cell proliferation; and positive regulation of transforming growth factor beta receptor signaling pathway. Located in extracellular space. Is expressed in pancreas mesenchyme. Orthologous to human LRG1 (leucine rich alpha-2-glycoprotein 1). [provided by Alliance of Genome Resources, Apr 2022]

Lrg1 Products(2)

mRNA Protein Name
NM_029796.2 NP_084072.1 leucine-rich alpha-2-glycoprotein precursor
NM_029796.2 NP_084072.1 leucine-rich alpha-2-glycoprotein precursor
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables transforming growth factor beta receptor binding IPI
IPI: Inferred from physical interaction
23868260 MGI
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within brown fat cell differentiation IDA
IDA: Inferred from direct assay
18492766 MGI
acts upstream of or within positive regulation of angiogenesis IDA
IDA: Inferred from direct assay
23868260 MGI
acts upstream of or within positive regulation of angiogenesis IGI
IGI: Inferred from genetic interaction
23868260 MGI
acts upstream of or within positive regulation of angiogenesis IMP
IMP: Inferred from mutant phenotype
23868260 MGI
acts upstream of or within positive regulation of endothelial cell proliferation IMP
IMP: Inferred from mutant phenotype
23868260 MGI
acts upstream of or within positive regulation of transforming growth factor beta receptor signaling pathway IGI
IGI: Inferred from genetic interaction
23868260 MGI
acts upstream of or within response to bacterium IEP
IEP: Inferred from expression pattern
23012479 MGI
Cellular Component GO Annotation Evidence Reference Source
located in extracellular space IDA
IDA: Inferred from direct assay
23868260 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

leucine-rich alpha-2-glycoprotein

Lrg1 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Reference
Intra
Lrg1 Q91XL1 Klk10 Mus musculus Q99M20
Anti Bait CoIP
38707515
Cross: Cross-species interaction Intra: Intraspecies interaction

Recombinant Lrg1 Proteins

Cat. No. Product Name Accession Purity
HY-P77987 LRG1 Protein, Mouse (HEK293, His) Q91XL1 (L33-L342) ≥95%

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS07784 LRG1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Lrg1 NCBI NCBI:116844
Macaca fascicularis Lrg1 NCBI NCBI:102118680