2. Gene
  3. LRG1 - leucine rich alpha-2-glycoprotein 1 Gene

LRG1 - leucine rich alpha-2-glycoprotein 1 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as LRG; HMFT1766

Gene ID: 116844 | Gene type: protein coding

About LRG1

Cytogenetic location: 19p13.3 Genomic coordinates (GRCh38): 19:4,536,402-4,540,036 (from NCBI)

This gene has 2 transcripts (splice variants), 289 orthologues and 22 paralogues. Biased expression in liver (RPKM 150.7), esophagus (RPKM 16.6) and 4 other tissues.

Summary

The leucine-rich repeat (LRR) family of proteins, including LRG1, have been shown to be involved in protein-protein interaction, signal transduction, and cell adhesion and development. LRG1 is expressed during granulocyte differentiation (O'Donnell et al., 2002 [PubMed 12223515]).[supplied by OMIM, Mar 2008]

LRG1 Products(1)

mRNA Protein Name
NM_052972.3 NP_443204.1 leucine-rich alpha-2-glycoprotein precursor

LRG1 Protein Structure

LRR_1

LRR_1: Leucine Rich Repeat (93 - 111)

LRR_8

LRR_8: Leucine rich repeat (116 - 176)

LRR_1

LRR_1: Leucine Rich Repeat (190 - 208)

LRR_8

LRR_8: Leucine rich repeat (213 - 272)

  • 0
  • 100
  • 200
  • 300
  • 347 a.a.
Protein Preferred Names Protein Names

leucine-rich alpha-2-glycoprotein

1300008B03Rik

Recombinant LRG1 Proteins

Cat. No. Product Name Accession Purity
HY-P70166 LRG1 Protein, Human (HEK293, His) AAH34389.1  (V36-Q347) ≥95%
HY-P70175 LRG1 Protein, Human (HEK293, Fc-His) P02750/AAH70198.1 (V36-Q347) ≥95%

Related Diseases

Diseases Alias
Appendicitis

Acute Appendicitis

Acute Appendicitis With Generalized Peritonitis

Acute Appendicitis Nos

Acute Appendicitis With Peritoneal Abscess

Appendiceal Inflammation

Appendicitis, Unqualified

Acute Appendix Inflammation

Acute Appendicitis With Diffuse Peritonitis Following Rupture Or Perforation

Acute Appendicitis With Free Peritonitis

Acute Appendicitis With Free Perforation To The Abdominal Cavity

Perforated Appendix With Generalised Peritonitis

Appendicitis With Perforation And Free Pus In The Peritoneal Cavity

Perforated Appendix With Localised Peritonitis

Acute Appendicitis With Contained Perforation To A Localised Abscess

Acute Appendicitis With Localised Peritonitis With Rupture Or Perforation

Acute Appendicitis With Localised Peritonitis Without Rupture Or Perforation

Acute Appendicitis With Perforation And Contained Peritonitis Into An Abscess

Appendicitis With Abscess

Appendicitis With Peritoneal Abscess

Ruptured Appendix Nos

Acute Appendicitis With No Perforation Or Abscess And No Visible Pus

Acute Appendicitis With No Specification If Perforated Or Not

Acute Appendicitis With Phlegmone
Cecal Disease

Cecal Diseases

Disorder Of Cecum
Communicating Hydrocephalus

Acquired Communicating Hydrocephalus
Hydrocephalus

Hydrocephalus, Nonsyndromic, Autosomal Recessive

Hydrocephalus, X-Linked

Hydrocephalus Adverse Event

Hydrocephaly Nos
Normal Pressure Hydrocephalus

Low Pressure Hydrocephalus

Hydrocephalus Normal Pressure

Hydrocephalus, Normal Pressure

Normal Pressure Hydrocephalus Nos

Nph - [Normal Pressure Hydrocephalus]

Normal Pressure Hydrocephaly
Cardiomyopathy, Dilated, 1e

Left Ventricular Noncompaction 9

Left Ventricular Noncompaction 5

Dilated Cardiomyopathy 1e

Dilated Cardiomyopathy 1s

CMD1E

Cdcd2

Cardiomyopathy, Dilated, 1y

CMD1Y

Cardiomyopathy, Dilated, 1s

CMD1S

Dilated Cardiomyopathy 1y

Dilated Cardiomyopathy With Conduction Defect 2

Dilated Cardiomyopathy With Conduction Disorder And Arrhythmia

Cardiomyopathy, Dilated, With Conduction Disorder And Arrhythmia

Cardiomyopathy, Dilated, With Conduction Defect 2

Cardiomyopathy Dilated With Conduction Defect Type 2

Cardiomyopathy, Dilated 1e

Cardiomyopathy, Dilated 1s

Cardiomyopathy, Dilated 1y

Left Ventricular Non-Compaction 5

LVNC5

Left Ventricular Non-Compaction 9

LVNC9

Cardiomyopathy, Dilated, Type 1e

Cardiomyopathy, Dilated, Type 1s

Cardiomyopathy, Dilated, Type 1y
Cardiomyopathy, Familial Hypertrophic, 1

Asymmetric Septal Hypertrophy

Familial Hypertrophic Cardiomyopathy

Hypertrophic Cardiomyopathy 1

CMH1

Hypertrophic Cardiomyopathy 19

CMH

Ventricular Hypertrophy, Hereditary

Ash

Hypertrophic Subaortic Stenosis, Idiopathic

Cardiomyopathy, Familial Hypertrophic

Cardiomyopathy, Hypertrophic, 1, Digenic

Cardiomyopathy, Familial Hypertrophic 1

Hcm

Hereditary Ventricular Hypertrophy

Idiopathic Hypertrophic Subaortic Stenosis

Hypertrophic Cardiomyopathy

Cardiomyopathy, Hypertrophic, Familial

Cardiomyopathy, Hypertrophic, 1

Familial Asymmetric Septal Hypertrophy

Heritable Hypertrophic Cardiomyopathy

Fhc

Cardiomyopathy, Hypertrophic, Familial, Type 1
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS07784 LRG1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus LRG1 RGD RGD:1359464
Macaca mulatta LRG1 VGNC VGNC:74394
Bos taurus LRG1 VGNC VGNC:30980
Felis catus LRG1 VGNC VGNC:102630
Canis familiaris LRG1 VGNC VGNC:42765
Mus musculus LRG1 MGD MGI:1924155
Macaca fascicularis LRG1 NCBI NCBI:102118680
Others LRG1 NCBI