1. Gene
  2. PAX8 - paired box 8 Gene

PAX8 - paired box 8 Gene

Homo sapiens

Also known as PAX-8

Gene ID: 7849 | Gene type: protein coding

About PAX8

Cytogenetic location: 2q14.1 Genomic coordinates (GRCh38): 2:113,215,997-113,278,921 (from NCBI)

This gene has 14 transcripts (splice variants), 167 orthologues, 50 paralogues and is associated with 85 phenotypes. Biased expression in thyroid (RPKM 261.2) and kidney (RPKM 40.3).

Summary

This gene encodes a member of the paired box (PAX) family of transcription factors. Members of this gene family typically encode proteins that contain a paired box domain, an octapeptide, and a paired-type homeodomain. This nuclear protein is involved in thyroid follicular cell development and expression of thyroid-specific genes. Mutations in this gene have been associated with thyroid dysgenesis, thyroid follicular carcinomas and atypical follicular thyroid adenomas. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Mar 2010]

PAX8 Products(4)

mRNA Protein Name
NM_003466.4 NP_003457.1 paired box protein Pax-8 isoform PAX8A
NM_013952.4 NP_039246.1 paired box protein Pax-8 isoform PAX8C
NM_013953.4 NP_039247.1 paired box protein Pax-8 isoform PAX8D
NM_013992.4 NP_054698.1 paired box protein Pax-8 isoform PAX8E
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables DNA binding IDA
IDA: Inferred from direct assay
8861958 GOA
enables DNA binding IMP
IMP: Inferred from mutant phenotype
9590296 GOA
enables DNA-binding transcription factor activity IDA
IDA: Inferred from direct assay
9388203 GOA
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IDA
IDA: Inferred from direct assay
9388203 GOA
enables protein binding IPI
IPI: Inferred from physical interaction
19010321 GOA
enables sequence-specific double-stranded DNA binding IDA
IDA: Inferred from direct assay
28473536 GOA
enables transcription cis-regulatory region binding IDA
IDA: Inferred from direct assay
15356023 GOA
Biological Process GO Annotation Evidence Reference Source
involved in DNA-templated transcription IDA
IDA: Inferred from direct assay
9590296 GOA
involved in branching involved in ureteric bud morphogenesis IEP
IEP: Inferred from expression pattern
1337742 GOA
involved in cellular response to gonadotropin stimulus IDA
IDA: Inferred from direct assay
15961562 GOA
involved in central nervous system development IEP
IEP: Inferred from expression pattern
15494458 GOA
involved in kidney development IEP
IEP: Inferred from expression pattern
15494458 GOA
involved in mesenchymal to epithelial transition involved in metanephros morphogenesis IEP
IEP: Inferred from expression pattern
8861958 GOA
involved in metanephric S-shaped body morphogenesis IEP
IEP: Inferred from expression pattern
1337742 GOA
involved in metanephric comma-shaped body morphogenesis IEP
IEP: Inferred from expression pattern
1337742 GOA
involved in metanephric epithelium development IEP
IEP: Inferred from expression pattern
7856737 GOA
involved in otic vesicle development IEP
IEP: Inferred from expression pattern
15494458 GOA
involved in positive regulation of DNA-templated transcription IDA
IDA: Inferred from direct assay
8413205 GOA
involved in positive regulation of thyroid hormone generation IMP
IMP: Inferred from mutant phenotype
15356023 GOA
involved in positive regulation of transcription by RNA polymerase II IDA
IDA: Inferred from direct assay
9388203 GOA
involved in regulation of thyroid-stimulating hormone secretion IMP
IMP: Inferred from mutant phenotype
15356023 GOA
involved in thyroid gland development IEP
IEP: Inferred from expression pattern
1337742 GOA
involved in thyroid gland development IMP
IMP: Inferred from mutant phenotype
9590296 GOA
Cellular Component GO Annotation Evidence Reference Source
located in nucleus IDA
IDA: Inferred from direct assay
9388203 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

PAX8 Protein Structure

PAX

PAX: 'Paired box' domain (9 - 133)

  • 0
  • 100
  • 200
  • 300
  • 398 a.a.
Protein Preferred Names Protein Names

paired box protein Pax-8

paired domain gene 8

Recombinant PAX8 Proteins

Cat. No. Product Name Accession Purity
HY-P74651 PAX8 Protein, Human (His) Q06710 (P2-S146) ≥95%

Related Diseases

Diseases Alias
Hypothyroidism, Congenital, Nongoitrous, 2

Thyroid Dysgenesis

CHNG2

Thyroid Hypoplasia

Thyroid Hemiagenesis

Thyroid Agenesis

Athyreotic Hypothyroidism

Rtsh

Thyrotropin Resistance

Hypothyroidism, Congenital, Due To Thyroid Dysgenesis Or Hypoplasia

Congenital Nongoitrous Hypothyroidism 2

Thyroid, Ectopic

Hypothyroidism, Congenital, Due To Thyroid Dysgenesis

Hypothyroidism, Athyreotic

Thyrotropin

Resistance To Thyrotropin

Congenital Hypothyroidism Due To Thyroid Dysgenesis Or Hypoplasia

Hypothyroidism, Congenital, Non-Goitrous, 2

Congenital Hypothyroidism Due To Thyroid Dysgenesis

Thyroid-Stimulating Hormone Resistance

Thyroid Ectopic

Ectopic Thyroid

Hypothyroidism, Congenital, Nongoitrous, 3

Thyroid Hormone Resistance Syndrome

Hypothyroidism, Congenital, Nongoitrous, 1

Athyreosis
Thyroid Ectopia
Congenital Hypothyroidism

Cretinism

Neonatal Hypothyroidism

Ch

Cht

Congenital Myxedema

Myxedema, Congenital

Endemic Cretinism

Congenital Iodine-Deficiency Syndrome

Fetal Iodine Deficiency Syndrome

Congenital Iodine-Deficiency Hypothyroidism Nos

Differentiated Thyroid Carcinoma

Papillary Or Follicular Thyroid Carcinoma

Well-Differentiated Thyroid Carcinoma

Differentiated Thyroid Gland Carcinoma

Hypothyroidism

Thyroid Diseases

Thyroid Disease

Thyroid Deficiency

Thyroid Insufficiency

Dysfunction Thyroid

Thyroid Dysfunction

Thyroid Gland Cancer

Thyroid Gland Carcinoma

Malignant Neoplasm Of Thyroid Gland

Malignant Tumour Of Thyroid Gland

Thyroid Neoplasm

Thyroid Neoplasms

Neoplasm Of Thyroid Gland

Thyroid Gland Neoplasm

Head And Neck Cancer, Thyroid

Neoplasm Of The Thyroid Gland

Cancer Of The Thyroid

Primary Malignant Neoplasm Of Thyroglossal Duct

Malignant Neoplasm Of Thyroglossal Duct

Primary Malignant Neoplasm Of Thyroid Gland

Thyroglossal Duct Cancer

Toxic Goitre Malignant Tumour

Cancerous Goitre

Endosalpingiosis
Goiter

Goitre

Follicular Adenoma

Follicular Adenoma Of The Thyroid Gland

Thyroid Follicular Adenoma

Adenoma Follicular

Follicular Thyroid Adenoma

Thyroid Gland Follicular Adenoma

Thyroid Gland Anaplastic Carcinoma

Anaplastic Thyroid Carcinoma

Anaplastic Thyroid Cancer

Thyroid Cancer, Anaplastic

Thyroid Carcinoma, Anaplastic

Thyroid Carcinoma Anaplastic

Ovarian Mesodermal Adenosarcoma

Ovarian Mullerian Adenosarcoma

Ovarian Adenosarcoma

Thymus Basaloid Carcinoma

Basaloid Carcinoma Of The Thymus

Thymic Basaloid Carcinoma

Mucinous Cystadenofibroma
Sarcomatoid Renal Cell Carcinoma

Renal Cell Carcinoma, Spindle Cell

Nephrogenic Adenoma

Nephrogenic Metaplasia

Cystadenofibroma
Bladder Clear Cell Adenocarcinoma

Bladder Mesonephric Adenocarcinoma

Clear Cell Adenocarcinoma Of Bladder

Urethra Clear Cell Adenocarcinoma

Clear Cell Adenocarcinoma Of The Urethra

Urethral Clear Cell Adenocarcinoma

Pendred Syndrome

Goiter-Deafness Syndrome

Deafness With Goiter

PDS

Thyroid Dyshormonogenesis 2b

Tdh2b

Autosomal Recessive Sensorineural Hearing Impairment And Goiter

Pendred'S Syndrome

Thyroid Hormonogenesis, Genetic Defect In, 2b

Hypothyroidism, Congenital, Due To Dyshormonogenesis, 2b

Congenital Hypothyroidism Due To Dyshormonogenesis 2b

Genetic Defect In Thyroid Hormonogenesis 2b

Autosomal Recessive Sensorineural Hearing Impairment, Enlarged Vestibular Aqueduct, And Goiter

Goiter-Hearing Loss Syndrome

Goitre-Deafness Syndrome

Goitre Deafness

Urethra Adenocarcinoma

Adenocarcinoma Of The Urethra

Urethral Adenocarcinoma

Epithelioid Type Angiomyolipoma

Epithelioid Angiomyolipoma

Ovarian Mucinous Neoplasm

Ovarian Mucinous Tumor

Malignant Ovarian Mucinous Neoplasm

Mucinous Tumor Of Ovary

Malignant Ovarian Mucinous Tumor

Benign Teratoma

Dermoid Cyst

Cystic Dermoid Choristoma

Dermoid Choristoma

Mature Cystic Teratoma

Dermoid Tumour

Teratoma, Benign

Dermoid Cyst Of Ovary

Fallopian Tube Carcinoma

Fallopian Tube Cancer

Cancer Of The Fallopian Tube

Carcinoma Of Fallopian Tube

Neoplasm Of Fallopian Tube

Fallopian Tube Neoplasms

Fallopian Tube Ca

Fallopian Tube Neoplasm

Malignant Neoplasm Of Uterine Tube

Malignant Tumor Of Fallopian Tube

Malignant Tumour Of Fallopian Tube

Tumor Of The Fallopian Tube

Tumor, Fallopian Tube, Malignant

Malignant Tumor Of Fallopian Tubes

Cancer Of Fallopian Tubes

Malignant Tubal Tumor

Tubal Cancer

Malignant Neoplasm Of Fallopian Tube

Primary Malignant Neoplasm Of Fallopian Tube

Cancer Of The Oviduct

Thymus Clear Cell Carcinoma

Clear Cell Carcinoma Of The Thymus

Thymic Clear Cell Carcinoma

Renal Pelvis Adenocarcinoma

Adenocarcinoma Of Renal Pelvis

Adenocarcinoma Of The Kidney Pelvis

Ovarian Seromucinous Carcinoma

Mixed Epithelial Carcinoma Of Ovary

Ovary Mixed Epithelial Carcinoma

Chronic Salpingitis
Vulvar Sebaceous Carcinoma
Atypical Follicular Adenoma
Rete Testis Neoplasm
Rete Testis Adenocarcinoma

Adenocarcinoma Of Rete Testis

Adenocarcinoma Of The Rete Testis

Hemangioblastoma

Capillary Hemangioblastoma

Thyroid Gland Mucoepidermoid Carcinoma

Mucoepidermoid Thyroid Carcinoma

Thyroid Angiosarcoma

Hemangiosarcoma Of The Thyroid

Angiomyolipoma

Angiomyolipoma Of Kidney

Thyroid Sarcoma

Sarcoma Of The Thyroid Gland

Thyroid Gland Sarcoma

Wolffian Duct Adenocarcinoma

Cervical Mesonephric Adenocarcinoma

Graves' Disease

Graves Disease

Exophthalmic Goiter

Basedow'S Disease

Grave'S Disease

Basedow Disease

Toxic Diffuse Goiter

Graves' Hyperthyroidism

Parry Disease

Autoimmune Hyperthyroidism

Toxic Multinodular Goiter

Thyroid Gland Follicular Carcinoma

Follicular Thyroid Carcinoma

Follicular Adenocarcinoma

Follicular Adenocarcinoma, Well Differentiated

Follicular Carcinoma

Thyroid Adenocarcinoma

Adenocarcinoma, Follicular

Ovarian Benign Neoplasm

Benign Ovarian Neoplasm

Carcinosarcoma

Mixed Tumor, Mullerian

Malignant Mixed Mesodermal Tumor

Malignant Mixed Mullerian Tumor

Mmmt

Mixed Tumor, Mesodermal

Mesodermal Mixed Tumor

Mixed Mesodermal Tumor

Mullerian Mixed Tumor

Mixed Mullerian Tumor

Malignant Mixed Müllerian Tumor

Mixed Müllerian Tumor

Mixed Tumor Mullerian

Mixed Tumor, Not Otherwise Specified

Rete Testis Adenoma
Urethral Diverticulum

Urethral Sacculation

Wolffian Duct Adenoma

Benign Mesonephroma

Mesonephric Adenoma

Mesonephroma, Benign

Fatwo

Female Adnexal Tumor Of Probable Wolffian Origin

Wat

Wolffian Adenoma

Wolffian Adnexal Tumor

Wolffian Tumor

Glycogen-Rich Clear Cell Breast Carcinoma

Glycogen-Rich Carcinoma

Mediastinum Sarcoma

Sarcoma Of Mediastinum

Nephrogenic Adenoma Of Urinary Bladder

Nephrogenic Adenoma Of The Urinary Bladder

Papillary Carcinoma

Carcinoma, Papillary

Carcinoma Papillary

Thyroid Malformation
Serous Cystadenocarcinoma

Serous Adenocarcinoma

Cystadenocarcinoma, Serous

Serous Carcinoma

Cystadenocarcinoma Serous

Kidney Benign Neoplasm

Renal And Ureteral Tumor

Benign Kidney Neoplasm

Fallopian Tube Adenocarcinoma

Adenocarcinoma Of The Fallopian Tube

Thyroid Cancer, Nonmedullary, 2

Thyroid Carcinoma, Follicular

Follicular Thyroid Carcinoma

NMTC2

Thyroid Cancer, Follicular

Thyroid Carcinoma, Follicular, Somatic

Ftc

Thyroid Cancer, Non-Medullary, 2

Thyroid Follicular Carcinoma

Follicular Thyroid Cancer

Cancer, Thyroid, Nonmedullary, Type 2

Thyroid Gland Adenocarcinoma

Follicular Carcinoma Of Unspecified Site

Moderately Differentiated Follicular Carcinoma Of Thyroid Gland

Pure Follicle Carcinoma Of Thyroid Gland

Pure Follicle Follicular Carcinoma Of Unspecified Site

Pure Follicular Carcinoma Of Thyroid Gland

Trabecular Follicular Carcinoma Of Thyroid Gland

Trabecular Follicular Carcinoma Of Unspecified Site

Well Differentiated Follicular Carcinoma Of Unspecified Site

Well Differentiated Follicular Carcinoma Of Thyroid Gland

Ovarian Large-Cell Neuroendocrine Carcinoma

Non-Small-Cell Type Neuroendocrine Carcinoma Of Ovary

Ovarian Large Cell Neuroendocrine Carcinoma

Bladder Benign Neoplasm
Endocervical Carcinoma

Carcinoma Of Endocervix

Carcinoma Of The Endocervix

Ovarian Mixed Germ Cell Neoplasm

Mixed Germ Cell Tumor Of Ovary

Ovarian Mixed Germ Cell Tumor

Collecting Duct Carcinoma

Kidney Medullary Carcinoma

Renal Medullary Carcinoma

Bdc

Bellini Carcinoma

Bellini Duct Carcinoma

Cdc

Collecting Duct Carcinoma Of The Kidney

Renal Cell Adenocarcinoma

Carcinoma Of Renal Collecting Duct

Renal Carcinoma, Collecting Duct Type

Renal Cell Carcinoma

Bellini'S Duct Carcinoma

Renal Collecting Duct Carcinoma

Adenocarcinoma Of Kidney

Nasal Cavity Olfactory Neuroblastoma

Olfactory Neuroblastoma Of The Nasal Cavity

Peritoneum Cancer

Peritoneal Neoplasm

Cancer Of Peritoneum

Malignant Tumor Of Peritoneum

Peritoneal Neoplasms

Combined Thymoma
Mixed Type Thymoma

Thymoma, Mixed Type

Thymoma, Type Ab

Benign Struma Ovarii
Epididymis Adenocarcinoma

Adenocarcinoma Of The Epididymis

Water-Clear Cell Adenoma
Epididymis Cancer

Malignant Tumor Of Epididymis

Malignant Epididymal Tumor

Malignant Neoplasm Of Epididymis

Neoplasm Of Epididymis

Thyroid Gland Disease

Abnormality Of The Thyroid Gland

Thyroid Diseases

Urethra Cancer

Cancer Of Urethra

Malignant Tumour Of Urethra

Malignant Urethral Neoplasm

Urethral Ca

Renal Adenoma

Renal Cell Adenoma

Peritoneal Serous Adenocarcinoma

Primary Peritoneal Serous Adenocarcinoma

Papillary Serous Adenocarcinoma

Micropapillary Serous Carcinoma

Serous Surface Papillary Carcinoma

Papillary Serous Carcinoma

Papillary Serous Cystadenocarcinoma

Thyroid Dyshormonogenesis 1

TDH1

Hypothyroidism, Congenital, Due To Dyshormonogenesis, 1

Genetic Defect In Thyroid Hormonogenesis 1

Thyroid Hormonogenesis, Genetic Defect In, 1

Iodine Accumulation, Transport, Or Trapping Defect

Iodide Accumulation, Transport, Or Trapping Defect

Chdh1

Congenital Hypothyroidism Due To Dyshormonogenesis Type 1

Iodine Accumulation, Transport Or Trapping Defect

Cystic Teratoma

Dermoid Cyst

Benign Teratoma

Perivascular Epithelioid Cell Tumor

Pecoma

Perivascular Epithelioid Cell Neoplasms

Neoplasm With Perivascular Epithelioid Cell Differentiation

Clear Cell Hidradenoma

Clear Cell Myoepithelioma

Eccrine Acrospiroma

Krukenberg Carcinoma

Krukenberg Tumor

Krukenberg Neoplasm

Krukenberg'S Tumor

Metanephric Adenoma
Adenofibroma
Endometrial Squamous Cell Carcinoma

Squamous Cell Carcinoma Of Endometrium

Peritoneal Mesothelioma

Malignant Mesothelioma Of Peritoneum

Advanced Malignant Mesothelioma Of Peritoneum

Advanced Malignant Peritoneal Mesothelioma

Advanced Peritoneal Malignant Mesothelioma

Ovarian Germ Cell Teratoma

Germ Cell Teratoma Of Ovary

Ovarian Teratoma

Clear Cell Adenocarcinoma

Mesonephroma

Water-Clear Cell Adenocarcinoma

Adenocarcinoma, Clear Cell

Malignant Mesonephroma

Mesonephroid Clear Cell Carcinoma

Mesonephroma, Malignant

Water-Clear Cell Carcinoma

Wolffian Duct Neoplasm

Adenocarcinoma Clear Cell

Mesonephric Tumor

Colloid Adenoma

Macrofollicular Adenoma

Ovarian Germ Cell Cancer

Ovarian Germ Cell Tumor

Malignant Germ Cell Tumor Of Ovary

Germ Cell Neoplasm Of Ovary

Germ Cell Tumor Of Ovary

Mogct

Malignant Ovarian Germ Cell Tumor

Malignant Ovarian Germ Cell Neoplasm

Thyroid Dyshormonogenesis 2a

TDH2A

Iodide Peroxidase Deficiency

Deficiency Of Iodide Peroxidase

Thyroid Peroxidase Deficiency

Genetic Defect In Thyroid Hormonogenesis 2a

Thyroid Hormonogenesis, Genetic Defect In, 2a

Hypothyroidism, Congenital, Due To Dyshormonogenesis, 2a

Chdh2a

Congenital Hypothyroidism Due To Dyshormonogenesis Type 2a

Thyroid Hormone Organification Defect 2

Tiod

Ovarian Mucinous Adenocarcinoma

Mucinous Carcinoma Of Ovary

Wilms Tumor 5

Wilms Tumor

WT5

Wilms Tumor Susceptibility-5

Wilms Tumor And Radial Bilateral Aplasia

Nephroblastoma

Wilms' Tumor

Wilms Tumor, Susceptibility To

Wtsl

Bilateral Radial Aplasia With Wilms Tumor

Embryonal Adenosarcoma

Embryonal Nephroma

Kidney Wilms Tumor

Kidney, Adenomyosarcoma, Embryonal

Kidney, Carcinosarcoma, Embryonal

Kidney, Embryoma

Kidney, Embryonal Mixed Tumor

Nephroma

Renal Adenosarcoma

Renal Cancer, Wilms

Renal Wilms Tumor

Tumor, Wilms

Hereditary Susceptibility To Wilms Tumor 5

Neuroendocrine Tumor

Neuroendocrine Neoplasm

Neuroendocrine Tumors

Carcinoma, Neuroendocrine

Thyroid Gland Medullary Carcinoma

Medullary Thyroid Carcinoma

Medullary Carcinoma Of The Thyroid Gland

Ultimobranchial Thyroid Tumor

Ultimobranchial Thyroid Tumour

Thyroid Cancer, Medullary

Cystinuria

CSNU

Cystinuria Type B

Cystinuria Type A

Cystinuria, Type I, Formerly

Csnu1, Formerly

Cystinuria, Type Ii, Formerly

Cystinuria, Type Iii, Formerly

Csnu3, Formerly

Cystinuria, Type Non-I, Formerly

Cystinuria-Lysinuria

Cystinuria-Lysinuria Syndrome

Csnu1

Csnu3

Cystinuria 1

Cystinuria Type A/B

Cystinuria Type I

Cystinuria Type Ii

Cystinuria Type Iii

Cystinuria Type Non-I

Cystinuria, Type A/B

Cystinuria Type 1

Cystinuria - Lysinuria

Csnu - [Cystinuria]

Cystine Disease

Ovarian Carcinosarcoma

Ovarian Malignant Mixed Mullerian Tumor

Mmmt Of The Ovary

Malignant Mixed Mullerian Tumor Of The Ovary

Ovarian Malignant Mixed Epithelial Mesenchymal Tumor

Ovarian Malignant Mesodermal Mixed Tumor

Ovarian Mmmt

Malignant Mixed Müllerian Tumor Of The Ovary

Ovarian Malignant Mixed Müllerian Tumor

Carcinosarcoma Of Ovary

Hypothyroidism, Thyroidal Or Athyroidal, With Spiky Hair And Cleft Palate

Bamforth-Lazarus Syndrome

Bamforth Syndrome

Hypothyroidism, Athyroidal, With Spiky Hair And Cleft Palate

Hypothyroidism Cleft Palate Hypothyroidism, Athyroidal, With Spiky Hair And Cleft Palate

Athyroidal Hypothyroidism-Spiky Hair-Cleft Palate Syndrome

Hypothyroidism-Cleft Palate Syndrome

BLS

Athyroidal Hypothyroidism With Spiky Hair And Cleft Palate

Mixed Cell Type Cancer

Malignant Mixed Neoplasm

Malignant Mixed Tumor

Mixed Neoplasm

Mixed Tumor, Malignant

Malignant Mixed Cancer

Mixed Tumor

Malignant Mixed Tumor, Not Otherwise Specified

Mixed Salivary Gland Tumor

Mixed Tumor, Not Otherwise Specified

Malignant Struma Ovarii

Struma Ovarii, Malignant

Endemic Goiter

Iodine-Deficiency-Related Endemic Goitre

Simple Goitre

Goiter, Endemic

Euthyroid Goiter

Renal Cell Carcinoma, Nonpapillary

Renal Cell Carcinoma

RCC

Nonpapillary Renal Cell Carcinoma

Clear Cell Renal Cell Carcinoma

Hypernephroma

Adenocarcinoma Of Kidney

Renal Carcinoma, Chromophobe, Somatic

Clear Cell Carcinoma Of Kidney

Clear-Cell Metastatic Renal Cell Carcinoma

Clear Cell Renal Carcinoma

Renal Cell Carcinoma, Somatic

Conventional Renal Cell Carcinoma

Conventional Renal Cell Carcinoma

Renal Clear Cell Carcinoma

Ccrcc

Hereditary Clear Cell Renal Cell Carcinoma

Carcinoma, Renal Cell

Renal Cell Carcinoma, Clear Cell, Somatic

Renal Cell Carcinoma, Clear Cell

Clear Cell Kidney Carcinoma

Clear Cell Rcc

Cystic-Multilocular Variant

Clear Cell Renal Cell Adenocarcinoma

Hereditary Clear Cell Renal Cell Adenocarcinoma

Common Renal Cell Carcinoma

Crcc

Renal Cell Carcinoma Non-Papillary

Carcinoma Renal Cell

Renal Cell Cancer

Carcinoma, Renal Cell, Nonpapillary

Prostatic Acinar Adenocarcinoma

Acinar Prostate Adenocarcinoma

Nephrogenic Adenoma Of The Urethra

Nephrogenic Adenoma Of Urethra

Ovarian Endodermal Sinus Tumor

Endodermal Sinus Tumor Of Ovary

Ovarian Yolk Sac Tumor

Endodermal Sinus Tumour Of Ovary

Ovarian Endodermal Sinus Tumour

Ovarian Yolk Sac Tumour

Multinodular Goiter
Ureterocele
Renal Oncocytoma

Oncocytoma, Renal

Oncocytoma Of Kidney

Renal Epithelial Oncocytic Tumor

Oncocytoma Kidney

Oncocytoma Renal

Kidney Oncocytoma

Ovarian Primitive Germ Cell Tumor
Glandular Cystitis

Cystitis Glandularis

Endocervical Adenocarcinoma

Endocervical Carcinoma

Gallbladder Signet Ring Cell Adenocarcinoma

Signet Ring Cell Carcinoma Of The Gallbladder

Papillary Adenocarcinoma

Infiltrating And Papillary Adenocarcinoma

Infiltrating Papillary Adenocarcinoma

Adenocarcinoma Papillary

Adenocarcinoma, Papillary

Thymic Carcinoma

Malignant Thymoma

Thymoma, Malignant

Cystadenocarcinoma
Appendix Cancer

Appendiceal Neoplasms

Cancer Of The Appendix

Malignant Neoplasm Of Appendix Vermiformis

Malignant Tumor Of Appendix

Malignant Tumor Of The Appendix

Malignant Neoplasm Of Appendix

Carcinoma Of The Appendix

Appendix Disease

Disorder Of Appendix

Appendix Adenocarcinoma

Cystadenocarcinoma

Mucinous Adenocarcinoma

Adenocarcinoma Of Appendix

Appendiceal Adenocarcinoma

Adenocarcinoma Of The Appendix

Colonic Type Adenocarcinoma

Nonmucinous Adenocarcinoma

Ovarian Serous Carcinoma

Ovarian Serous Adenocarcinoma

Hypothyroidism, Congenital, Nongoitrous, 1

Tsh Resistance

CHNG1

Hypothyroidism Due To Tsh Receptor Mutations

Thyrotropin Resistance

Thyroid-Stimulating Hormone

Rtsh

Hypothyroidism Due To Unresponsiveness To Thyrotropin

Congenital Nongoitrous Hypothyroidism 1

Thyroid-Stimulating Hormone, Resistance To

Hypothyroidism, Nonautoimmune

Hypothyroidism, Congenital, Due To Tsh Resistance

Hypothyroidism, Congenital, Non-Goitrous, 1

Congenital Hypothyroidism Due To Tsh Resistance

Non-Autoimmune Hypothyroidism

Thyroid-Stimulating Hormone Resistance

Hypothyroidism, Congenital, Nongoitrous, Type 1

Hypothyroidism, Congenital, Nongoitrous, 3

Thyroid Hormone Resistance Syndrome

Perivascular Tumor

Malignant Perivascular Cancer

Uterus Perivascular Epithelioid Cell Tumor

Uterine Corpus Pecoma

Laryngeal Neuroendocrine Tumor

Laryngeal Neuroendocrine Tumour

Neuroendocrine Tumor Of Larynx

Neuroendocrine Tumour Of Larynx

Neuroendocrine Neoplasm Of Larynx

Thymus Large Cell Carcinoma

Large Cell Carcinoma Of The Thymus

Thymic Large Cell Neuroendocrine Carcinoma

Papillary Adenoma

Glandular Papilloma

Adenoma

Mucinous Adenocarcinoma

Mucin-Producing Adenocarcinoma

Mucin-Secreting Adenocarcinoma

Mucin-Secreting Carcinoma

Mucous Carcinoma

Pseudomyxoma Peritonei With Unknown Primary Site

Adenocarcinoma, Mucinous

Female Reproductive Endometrioid Cancer

Endometrioid Tumor

Endometrioid Neoplasm

Female Reproductive Endometrioid Neoplasm

Ovary Adenocarcinoma

Ovarian Adenocarcinoma

Adenocarcinoma Of The Ovary

Ovarian Adenoacanthoma

Adenocarcinoma Of Ovary

Mixed Germ Cell Cancer

Mixed Germ Cell Tumor

Mixed Germ Cell Neoplasm

Mixed Germ Cell Tumour

Mixed Teratoma And Seminoma

Colon Leiomyosarcoma

Colonic Leiomyosarcoma

Alveolar Soft Part Sarcoma

ASPS

Alveolar Soft-Part Sarcoma

Sarcoma, Alveolar Soft Part

Alveolar Soft Tissue Sarcoma

Sarcoma Alveolar Soft Part

Adult Alveolar Soft-Part Sarcoma

Childhood Alveolar Soft-Part Sarcoma

Endometrial Adenocarcinoma

Endometrial Endometrioid Adenocarcinoma

Endometrial Adenoacanthoma

Endometrial Endometrioid Adenocarcinoma, Variant With Squamous Differentiation

Adenocarcinoma Of Endometrium

Adenocarcinoma Of The Endometrium

Adenocarcinoma Of Uterus

Endometrial Endometrioid Adenocarcinoma With Squamous Differentiation

Endometrioid Adenoma Or Carcinoma

Endometrioid Adenomas And Carcinomas

Endometrioid Carcinoma Of Endometrium

Endometrium Adenocarcinoma

Urethral Benign Neoplasm

Urethral Neoplasms

Neoplasm Of Urethra

Neoplasm. Urethra

Urethral Neoplasm

Urethral Carcinoma

Malignant Neoplasm Of Urethra

Renal Cell Carcinoma, Papillary, 1

Papillary Renal Cell Carcinoma

Hereditary Papillary Renal Cell Carcinoma

Papillary Renal Cell Carcinoma, Sporadic

Papillary Renal Cell Adenocarcinoma

RCCP

RCCP1

Renal Cell Carcinoma, Papillary

Renal Cell Carcinoma, Papillary, 1, Familial And Somatic

Chromophil Carcinoma Of Kidney

Papillary Kidney Carcinoma

Sporadic Papillary Renal Cell Carcinoma

Chromophil Renal Cell Carcinoma

Papillary Renal Carcinoma, Malignant -

Papillary Renal Cell Carcinoma, Bilateral -

Papillary Renal Cell Carcinoma, Familial -

Papillary Renal Cell Carcinoma, Multiple -

Papillary Renal Cell Carcinoma, Sporadic -

Renal Adenocarcinoma

Chromophil Rcc

Hprcc

Renal Cell Carcinoma Papillary

Chromophilic Renal Cell Carcinoma

Prcc

Carcinoma, Renal Cell, Papillary, Type 1

Type 1 Papillary Renal Cell Carcinoma

Renal Cell Carcinoma

Hereditary Papillary Renal Carcinoma

Ovarian Serous Cystadenofibroma
Ovarian Cystadenocarcinoma

Cystadenocarcinoma Of Ovary

Cystadenocarcinoma Of The Ovary

Malignant Ovarian Surface Epithelial-Stromal Neoplasm

Malignant Ovarian Surface Epithelial-Stromal Tumor

Epithelioid Cell Synovial Sarcoma

Synovial Sarcoma, Epithelioid Cell

Epithelioid Synovial Sarcoma

Endocrine Organ Benign Neoplasm
Lymphohistiocytoid Mesothelioma
Ovarian Serous Adenofibroma
Papillary Adenofibroma
Chromophobe Renal Cell Carcinoma

Chromophobe Adenocarcinoma

Chromophobe Carcinoma Of Kidney

Kidney Chromophobe

Renal Cell Carcinoma, Chromophobe Cell

Crcc

Chrcc

Chromophobe Renal Cell Adenocarcinoma

Chromophobe Renal Carcinoma

Chromophobe Carcinoma

Fallopian Tube Endometrioid Adenocarcinoma

Endometrioid Carcinoma Of The Fallopian Tube

Fallopian Tube Endometrioid Cancer

Fallopian Tube Endometrioid Neoplasm

Fallopian Tube Endometrioid Tumor

Subacute Lymphocytic Thyroiditis
Ovarian Serous Cystadenocarcinoma

Serous Cystadenoma

Cystadenoma Serous

Cystadenoma, Serous

Wilms Tumor 1

Nephroblastoma

Wilms Tumor

WT1

Wilms' Tumor

Bilateral Wilms Tumor

Wilms Tumor, Type 1

Wilms Tumor, Somatic

Adult Nephroblastoma

Wt1 Disorder

Renal Embryonic Tumor

Adult Kidney Wilms Tumor

Childhood Kidney Wilms Tumor

Nonanaplastic Kidney Wilms Tumor

Renal Hypodysplasia/Aplasia 1

Renal Agenesis

Renal Adysplasia

Renal Aplasia

RHDA1

Hereditary Renal Aplasia

Hra

Hereditary Urogenital Adysplasia

Hypodysplasia/Aplasia, Renal, Type 1

Congenital Absence Of Kidneys Syndrome

Congenital Absence Of Kidney

Aplastic Kidney

Cervix Carcinoma

Cancer Of Cervix

Carcinoma Of Cervix

Carcinoma Cervix Uteri

Carcinoma Of The Cervix Uteri

Cakut

Renal Or Urinary Tract Malformation

Congenital Anomalies Of Kidney And Urinary Tract

Congenital Anomaly Of Kidney And Urinary Tract

Congenital Anomalies Of The Kidney And Urinary Tract

Kidney And Urinary Tract, Anomalies, Congenital

Renal Hypodysplasia, Nonsyndromic, 1

Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Orthologs Information

Species Symbol Source ID
Mus musculus PAX8 MGD MGI:97492
Bos taurus PAX8 VGNC VGNC:32599
Canis familiaris PAX8 VGNC VGNC:44279
Rattus norvegicus PAX8 RGD RGD:620434
Felis catus PAX8 VGNC VGNC:68702
Macaca mulatta PAX8 VGNC VGNC:75767
Others PAX8 NCBI