CCDC28B - coiled-coil domain containing 28B Gene

Homo sapiens (human)

Gene ID: 79140 | Gene type: protein coding

About CCDC28B

Summary

The product of this gene localizes to centrosomes and basal bodies. The protein colocalizes with several proteins associated with Bardet-Biedl syndrome (BBS) and participates in the regulation of cilia development. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]

CCDC28B Products(1)

mRNA	Protein	Name
XM_054338690.1	XP_054194665.1	coiled-coil domain-containing protein 28B isoform X3

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	16327777	GOA

Biological Process GO Annotation	Evidence	Reference	Source
involved in cilium assembly	IMP IMP: Inferred from mutant phenotype	23015189	GOA

Cellular Component GO Annotation	Evidence	Reference	Source
located in centrosome	IDA IDA: Inferred from direct assay	16327777	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

coiled-coil domain-containing protein 28B

CCDC28B Protein-protein interaction Information

Type Cross Intra	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Reference
Intra	CCDC28B	Q9BUN5	BBS4	Homo sapiens	Q96RK4	Y2H	16327777
Intra	CCDC28B	Q9BUN5	BBS4	Homo sapiens	Q96RK4	Anti Tag CoIP	16327777
Intra	CCDC28B	Q9BUN5	ATRIP	Homo sapiens	Q8WXE1	Validated Y2H	25416956
Intra	CCDC28B	Q9BUN5	ATRIP	Homo sapiens	Q8WXE1	Y2H Prey Pooling	25416956

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS02062	CCDC88B Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

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