St13 - ST13, Hsp70 interacting protein Gene

Rattus norvegicus

Gene ID: 81800 | Gene type: protein coding

About St13

Summary

Enables several functions, including HSP70 protein binding activity; chaperone binding activity; and dATP binding activity. Involved in chaperone cofactor-dependent protein refolding and negative regulation of protein refolding. Located in cytosol. Part of protein-containing complex. Orthologous to several human genes including ST13 (ST13 HSP70 interacting protein). [provided by Alliance of Genome Resources, Apr 2022]

St13 Products(1)

mRNA	Protein	Name
NM_031122.2	NP_112384.1	hsc70-interacting protein

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables Hsp70 protein binding	IDA IDA: Inferred from direct assay	7585962	RGD
enables Hsp70 protein binding	IPI IPI: Inferred from physical interaction	9528774	RGD
enables dATP binding	IDA IDA: Inferred from direct assay	9183013	RGD
enables identical protein binding	IPI IPI: Inferred from physical interaction	7585962	RGD
enables protein binding	IPI IPI: Inferred from physical interaction	21808025	RGD
enables protein domain specific binding	IDA IDA: Inferred from direct assay	7585962	RGD
enables protein domain specific binding	IPI IPI: Inferred from physical interaction	9528774	RGD
enables protein-containing complex binding	IDA IDA: Inferred from direct assay	7585962	RGD
enables protein-folding chaperone binding	IPI IPI: Inferred from physical interaction	9528774	RGD
enables unfolded protein binding	IDA IDA: Inferred from direct assay	9183013	RGD

Biological Process GO Annotation	Evidence	Reference	Source
involved in chaperone cofactor-dependent protein refolding	IDA IDA: Inferred from direct assay	7585962	RGD
involved in negative regulation of protein refolding	IDA IDA: Inferred from direct assay	9183013	RGD

Cellular Component GO Annotation	Evidence	Reference	Source
part of protein-containing complex	IDA IDA: Inferred from direct assay	7585962	RGD

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

hsc70-interacting protein

hip	protein ST13 homolog
suppression of tumorigenicity 13 (colon carcinoma) Hsp70-interacting protein

St13 Protein-protein interaction Information

Type Cross Intra	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Reference
Intra	St13	P50503	Esr1	Rattus norvegicus	P06211	Anti Bait CoIP	21808025
Intra	St13	P50503	St13	Rattus norvegicus	P50503	SAXS	23812373
Intra	St13	P50503	St13	Rattus norvegicus	P50503	X-Ray Diffraction	23812373
Intra	St13	P50503	Bag1	Rattus norvegicus	B0K019	Anti Bait CoIP	21808025

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS13843	ST13 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	St13	NCBI	NCBI:6767
Macaca fascicularis	St13	NCBI	NCBI:102133241
Mus musculus	St13	NCBI	NCBI:70356

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