DRC7 - dynein regulatory complex subunit 7 Gene

Homo sapiens

Also known as FAP50; CFAP50; CCDC135; C16orf50

Gene ID: 84229 | Gene type: protein coding

About DRC7

Cytogenetic location: 16q21 Genomic coordinates (GRCh38): 16:57,694,806-57,731,805 (from NCBI)

This gene has 10 transcripts (splice variants) and 139 orthologues. Restricted expression toward testis (RPKM 24.8).

Summary

Predicted to be involved in flagellated sperm motility. Located in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]

DRC7 Products(3)

mRNA	Protein	Name
NM_001289162.2	NP_001276091.1	dynein regulatory complex subunit 7 isoform a
NM_001289163.2	NP_001276092.1	dynein regulatory complex subunit 7 isoform b
NM_032269.6	NP_115645.4	dynein regulatory complex subunit 7 isoform a

Gene Ontology

Molecular Function

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	24407287	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

dynein regulatory complex subunit 7

coiled-coil domain containing 135

Related Diseases

Diseases

Alias

Polycystic Kidney Disease 2 With Or Without Polycystic Liver Disease

Polycystic Kidney Disease 2	PKD2
Polycystic Kidney Disease, Adult, Type Ii	Apkd2
Polycystic Kidney Disease, Type 2	Adpkd2
Adult Polycystic Kidney Disease Type 2	Autosomal Dominant Polycystic Kidney Disease 2
Pkd-2	Polycystic Kidney Disease Adult Type Ii
Polycystic Kidney Type 2 Autosomal Dominant Disease	Kidney Disease, Polycystic, Type 2

Bardet-Biedl Syndrome 1

BBS1	Bardet-Biedl Syndrome 1, Modifier Of
Bardet-Biedl Syndrome	BBS
Bardet-Biedl Syndrome, Type 1	Laurence-Moon-Bardet-Biedl Syndrome

Primary Ciliary Dyskinesia

Immotile Cilia Syndrome	Kartagener Syndrome
Dextrocardia Bronchiectasis And Sinusitis	Pcd
Ciliary Motility Disorders	Ciliary Motility Disorder
Immotile Ciliary Syndrome	Ciliary Dyskinesia Primary
Ics	Polynesian Bronchiectasis
Dextrocardia-Bronchiectasis-Sinusitis Syndrome	Immotile Cilia Syndrome, Kartagener Type
Primary Ciliary Dyskinesia And Situs Inversus	Primary Ciliary Dyskinesia, Kartagener Type
Siewert Syndrome	Dyskinesia, Ciliary, Primary

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS03993	DRC7 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Felis catus	DRC7	VGNC	VGNC:61625
Bos taurus	DRC7	VGNC	VGNC:28206
Macaca mulatta	DRC7	VGNC	VGNC:71905
Canis familiaris	DRC7	VGNC	VGNC:40092
Rattus norvegicus	DRC7	RGD	RGD:1565601
Mus musculus	DRC7	MGD	MGI:2685616

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