2. Gene
  3. LZIC - leucine zipper and CTNNBIP1 domain containing Gene

LZIC - leucine zipper and CTNNBIP1 domain containing Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens
Gene ID: 84328 | Gene type: protein coding

About LZIC

Cytogenetic location: 1p36.22 Genomic coordinates (GRCh38): 1:9,922,118-9,943,391 (from NCBI)

This gene has 5 transcripts (splice variants), 200 orthologues and 1 paralogue. Ubiquitous expression in testis (RPKM 8.7), colon (RPKM 7.1) and 25 other tissues.

Summary

Predicted to enable beta-catenin binding activity. Predicted to be involved in response to ionizing radiation. [provided by Alliance of Genome Resources, Apr 2022]

LZIC Products(5)

mRNA Protein Name
NM_001316973.2 NP_001303902.1 protein LZIC isoform a
NM_001316974.2 NP_001303903.1 protein LZIC isoform b
NM_001316975.2 NP_001303904.1 protein LZIC isoform c
NM_001316976.2 NP_001303905.1 protein LZIC isoform d
NM_032368.5 NP_115744.2 protein LZIC isoform a
Gene Ontology
  • Molecular Function
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
32296183 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

LZIC Protein Structure

ICAT

ICAT: Beta-catenin-interacting protein ICAT (113 - 190)

  • 0
  • 100
  • 190 a.a.
Protein Preferred Names Protein Names

protein LZIC

leucine zipper and CTNNBIP1 domain-containing protein

Related Diseases

Diseases Alias
Schnyder Corneal Dystrophy

Schnyder Crystalline Corneal Dystrophy

SCCD

Corneal Dystrophy, Crystalline, Of Schnyder

Corneal Dystrophy, Schnyder Type

Corneal Dystrophy Crystalline Of Schnyder

Crystalline Stromal Dystrophy

Hereditary Crystalline Stromal Dystrophy Of Schnyder

Scd

Corneal Dystrophy, Schnyder

Schnyder Crystalline Dystrophy Sine Crystals

Dystrophy, Corneal, Crystalline, Schnyder
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS07931 LZIC Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus LZIC VGNC VGNC:106811
Canis familiaris LZIC VGNC VGNC:42903
Felis catus LZIC VGNC VGNC:107578
Mus musculus LZIC MGD MGI:1916401
Macaca mulatta LZIC VGNC VGNC:74306
Rattus norvegicus LZIC RGD RGD:1309253