2. Gene
  3. Sfrp1 - secreted frizzled-related protein 1 Gene

Sfrp1 - secreted frizzled-related protein 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as sFRP-1

Gene ID: 84402 | Gene type: protein coding

About Sfrp1

Primary_assembly 16: 68,575,763-68,614,286 reverse strand.mRatBN7.2:CM026989.1

This gene has 1 transcript (splice variant), 223 orthologues, 15 paralogues and is associated with 10 phenotypes. Biased expression in Kidney (RPKM 136.3), Spleen (RPKM 19.3) and 9 other tissues.

Summary

Predicted to enable several functions, including Wnt-protein binding activity; Frizzled binding activity; and heparin binding activity. Involved in several processes, including cellular response to prostaglandin E stimulus; negative regulation of osteoclast differentiation; and osteoblast differentiation. Predicted to be located in cell surface; collagen-containing extracellular matrix; and cytosol. Predicted to be active in extracellular space. Orthologous to human SFRP1 (secreted Frizzled related protein 1). [provided by Alliance of Genome Resources, Apr 2022]

Sfrp1 Products(1)

mRNA Protein Name
NM_001276712.2 NP_001263641.2 secreted frizzled-related protein 1 precursor

Sfrp1 Protein Structure

CRD_SFRP1

CRD_SFRP1: cd07443 (51 - 174)

NTR_Sfrp1_like

NTR_Sfrp1_like: cd03580 (182 - 305)

  • 0
  • 100
  • 200
  • 314 a.a.
Protein Preferred Names Protein Names

secreted frizzled-related protein 1

Related Agents

Pre-clinical Phase
Bioactive Molecules (5)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-10858 WAY 316606 Inhibitor 99.24% Unkown
HY-10858A WAY 316606 hydrochloride Inhibitor / Unkown
HY-RS12772 SFRP1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS12773 Sfrp1 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS12774 Sfrp1 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Sfrp1 NCBI NCBI:6422
Mus musculus Sfrp1 NCBI NCBI:20377