2. Gene
  3. ADGRG7 - adhesion G protein-coupled receptor G7 Gene

ADGRG7 - adhesion G protein-coupled receptor G7 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as GPR128

Gene ID: 84873 | Gene type: protein coding

About ADGRG7

Cytogenetic location: 3q12.2 Genomic coordinates (GRCh38): 3:100,609,601-100,695,479 (from NCBI)

This gene has 5 transcripts (splice variants), 193 orthologues and 42 paralogues. Biased expression in duodenum (RPKM 18.5), small intestine (RPKM 17.4) and 2 other tissues.

Summary

Predicted to enable G protein-coupled receptor activity. Predicted to be involved in adenylate cyclase-activating G protein-coupled receptor signaling pathway. Predicted to be integral component of membrane. Predicted to be integral component of plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

ADGRG7 Products(2)

mRNA Protein Name
NM_001308362.1 NP_001295291.1 adhesion G-protein coupled receptor G7 isoform 2 precursor
NM_032787.3 NP_116176.2 adhesion G-protein coupled receptor G7 isoform 1 precursor
Gene Ontology
  • Molecular Function
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
25416956 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

ADGRG7 Protein Structure

GPS

GPS: GPCR proteolysis site, GPS, motif (380 - 422)

7tm_2

7tm_2: 7 transmembrane receptor (Secretin family) (433 - 715)

  • 0
  • 200
  • 400
  • 600
  • 797 a.a.
Protein Preferred Names Protein Names

adhesion G-protein coupled receptor G7

G-protein coupled receptor 128

Related Diseases

Diseases Alias
Fibrogenesis Imperfecta Ossium

Baker'S Disease
Osteogenesis Imperfecta, Type Xvii

Osteogenesis Imperfecta Type 17

OI17

Osteogenesis Imperfecta Type Xvii

Osteogenesis Imperfecta 17
Osteogenesis Imperfecta, Type Iv

Osteogenesis Imperfecta Type 4

Osteogenesis Imperfecta Type Iv

OI4

Oi, Type Iv

Osteogenesis Imperfecta With Normal Sclerae

Oi Type Iv

Oi Type 4

Osteogenesis Imperfecta With Normal Sclera

Common Variable Oi With Normal Sclerae

Osteogenesis Imperfecta 4

Oi-Iv
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS00360 ADGRG7 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus ADGRG7 MGD MGI:2441732
Canis familiaris ADGRG7 VGNC VGNC:37649
Bos taurus ADGRG7 VGNC VGNC:25670
Macaca mulatta ADGRG7 VGNC VGNC:69636
Rattus norvegicus ADGRG7 RGD RGD:1307217
Felis catus ADGRG7 VGNC VGNC:59637