FRMD5 - FERM domain containing 5 Gene

Homo sapiens

Also known as NEDEMA

Gene ID: 84978 | Gene type: protein coding

About FRMD5

Cytogenetic location: 15q15.3 Genomic coordinates (GRCh38): 15:43,870,764-44,199,473 (from NCBI)

This gene has 12 transcripts (splice variants), 306 orthologues and 10 paralogues. Biased expression in brain (RPKM 6.9), heart (RPKM 4.6) and 4 other tissues.

Summary

Enables Integrin binding activity and protein kinase binding activity. Involved in negative regulation of cell motility; positive regulation of cell adhesion; and regulation of cell migration. Located in adherens junction. [provided by Alliance of Genome Resources, Apr 2022]

FRMD5 Products(7)

mRNA	Protein	Name
NM_001286490.2	NP_001273419.1	FERM domain-containing protein 5 isoform 3
NM_001286491.2	NP_001273420.1	FERM domain-containing protein 5 isoform 4
NM_001322949.2	NP_001309878.1	FERM domain-containing protein 5 isoform 6
NM_001322950.2	NP_001309879.1	FERM domain-containing protein 5 isoform 7
NM_001322951.2	NP_001309880.1	FERM domain-containing protein 5 isoform 8
NM_001411124.1	NP_001398053.1	FERM domain-containing protein 5 isoform 9
NM_032892.5	NP_116281.2	FERM domain-containing protein 5 isoform 2

FRMD5 Protein Structure

FERM_N

FERM_M

FERM_C

0
100
200
300
400
500
570 a.a.

Protein Preferred Names

Protein Names

FERM domain-containing protein 5

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS05103	FRMD5 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Bos taurus	FRMD5	VGNC	VGNC:29116
Canis familiaris	FRMD5	VGNC	VGNC:40982
Macaca mulatta	FRMD5	VGNC	VGNC:72797
Felis catus	FRMD5	VGNC	VGNC:62362
Rattus norvegicus	FRMD5	RGD	RGD:1561554
Mus musculus	FRMD5	MGD	MGI:2442557

Name
Email *

	Sorry, but the email address you supplied was invalid.