SLX9 - SLX9 ribosome biogenesis factor Gene

Homo sapiens

Also known as PRED56; FAM207A; C21orf70

Gene ID: 85395 | Gene type: protein coding

About SLX9

This gene has 5 transcripts (splice variants) and 194 orthologues. Ubiquitous expression in testis (RPKM 3.9), spleen (RPKM 3.7) and 25 other tissues.

Summary

Predicted to be involved in maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA). Predicted to be located in nucleolus. Predicted to be part of 90S preribosome and preribosome, small subunit precursor. [provided by Alliance of Genome Resources, Apr 2022]

SLX9 Products(7)

mRNA	Protein	Name
NM_001316983.2	NP_001303912.1	ribosome biogenesis protein SLX9 homolog isoform 2
NM_001316984.2	NP_001303913.1	ribosome biogenesis protein SLX9 homolog isoform 3
NM_001316985.2	NP_001303914.1	ribosome biogenesis protein SLX9 homolog isoform 4
NM_001316986.2	NP_001303915.1	ribosome biogenesis protein SLX9 homolog isoform 5
NM_001316987.2	NP_001303916.1	ribosome biogenesis protein SLX9 homolog isoform 6
NM_001316988.2	NP_001303917.1	ribosome biogenesis protein SLX9 homolog isoform 7
NM_058190.4	NP_478070.1	ribosome biogenesis protein SLX9 homolog isoform 1

Gene Ontology

Molecular Function

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	25416956	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

SLX9 Protein Structure

SLX9

0
100
200
230 a.a.

Protein Preferred Names

Protein Names

ribosome biogenesis protein SLX9 homolog

family with sequence similarity 207 member A

SLX9 Protein-protein interaction Information

Type Cross Intra	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Reference
Intra	SLX9	Q9NSI2	GOLGA6L9	Homo sapiens	A6NEM1	Y2H Array	32296183
Intra	SLX9	Q9NSI2	GOLGA6L9	Homo sapiens	A6NEM1	Y2H Prey Pooling	32296183
Intra	SLX9	Q9NSI2	GOLGA2	Homo sapiens	Q08379	Y2H Prey Pooling	25416956
Intra	SLX9	Q9NSI2	PICK1	Homo sapiens	Q9NRD5	Y2H Prey Pooling	32296183
Intra	SLX9	Q9NSI2	PICK1	Homo sapiens	Q9NRD5	Y2H Array	32296183

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases

Alias

Glutamate Formiminotransferase Deficiency

Formiminoglutamic Aciduria	Formiminotransferase Deficiency
FIGLU-URIA	Arakawa Syndrome 1
Formiminoglutamic Acidemia	Formiminotransferase Cyclodeaminase Deficiency
Formiminotransferase Deficiency Syndrome	Ftcd Deficiency
Formiminoglutamicaciduria	Figluria

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS13391	SLX9 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Bos taurus	SLX9	VGNC	VGNC:28782
Felis catus	SLX9	VGNC	VGNC:102697
Canis familiaris	SLX9	VGNC	VGNC:40651
Rattus norvegicus	SLX9	RGD	RGD:1311257
Mus musculus	SLX9	MGD	MGI:1916334
Macaca mulatta	SLX9	VGNC	VGNC:72273

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