Tfpt - TCF3 fusion partner Gene

Rattus norvegicus

Also known as Amida

Gene ID: 85423 | Gene type: protein coding

About Tfpt

Summary

Enables DNA binding activity and protein kinase binding activity. Involved in apoptotic process; male gonad development; and positive regulation of apoptotic process. Located in cytoplasm and nucleus. Colocalizes with actin filament. Orthologous to human TFPT (TCF3 fusion partner). [provided by Alliance of Genome Resources, Apr 2022]

Tfpt Products(3)

mRNA	Protein	Name
NM_001398653.1	NP_001385582.1	TCF3 fusion partner homolog isoform 2
NM_001398655.1	NP_001385584.1	TCF3 fusion partner homolog isoform 3
NM_138870.2	NP_620225.2	TCF3 fusion partner homolog isoform 1

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables DNA binding	IDA IDA: Inferred from direct assay	12841360	RGD
enables protein binding	IPI IPI: Inferred from physical interaction	10644725	RGD
enables protein kinase binding	IPI IPI: Inferred from physical interaction	12841360	RGD
enables protein-containing complex binding	IDA IDA: Inferred from direct assay	10644725	RGD

Biological Process GO Annotation	Evidence	Reference	Source
involved in apoptotic process	IDA IDA: Inferred from direct assay	16229834	RGD
involved in male gonad development	IEP IEP: Inferred from expression pattern	11606057	RGD
involved in positive regulation of apoptotic process	IDA IDA: Inferred from direct assay	10644725	RGD

Cellular Component GO Annotation	Evidence	Reference	Source
located in actin filament	IDA IDA: Inferred from direct assay	16229834	RGD
located in cytoplasm	IDA IDA: Inferred from direct assay	16229834	RGD
located in nucleus	IDA IDA: Inferred from direct assay	16229834	RGD

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

TCF3 fusion partner homolog

TCF3 (E2A) fusion partner (in childhood leukemia)

protein amida

Tfpt Protein-protein interaction Information

Type Cross Intra	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Reference
Intra	Tfpt	Q9JMG6	Pawr	Rattus norvegicus	Q62627	Y2H	16229834
Intra	Tfpt	Q9JMG6	Pawr	Rattus norvegicus	Q62627	IF	16229834

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS14429	TFPT Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Tfpt	NCBI	NCBI:29844

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