Pawr - pro-apoptotic WT1 regulator Gene

Rattus norvegicus

Also known as Par4; Par-4

Gene ID: 64513 | Gene type: protein coding

About Pawr

Summary

Enables actin binding activity; protein kinase C binding activity; and protein Phosphatase 1 binding activity. Involved in several processes, including detection of stimulus involved in sensory perception of pain; positive regulation of hydrolase activity; and regulation of cellular extravasation. Located in axon; cytoplasm; and neuronal cell body. Colocalizes with actin filament. Biomarker of mental depression; middle cerebral artery infarction; transient cerebral ischemia; and visual epilepsy. Orthologous to human PAWR (pro-apoptotic WT1 regulator). [provided by Alliance of Genome Resources, Apr 2022]

Pawr Products(1)

mRNA	Protein	Name
NM_033485.3	NP_277020.2	PRKC apoptosis WT1 regulator protein

Protein Preferred Names

Protein Names

PRKC apoptosis WT1 regulator protein

PRKC, apoptosis, WT1, regulator	Prostate apoptosis response protein 4
par-4 induced by effectors of apoptosis	prostate apoptosis response 4 protein
transcriptional repressor Par-4-like protein PAWR

Pawr Protein-protein interaction Information

Type Cross Intra	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Reference
Intra	Pawr	Q62627	Tfpt	Rattus norvegicus	Q9JMG6	Anti Tag CoIP	16229834
Intra	Pawr	Q62627	Tfpt	Rattus norvegicus	Q9JMG6	Y2H	16229834
Intra	Pawr	Q62627	Tfpt	Rattus norvegicus	Q9JMG6	Anti Bait CoIP	16229834
Intra	Pawr	Q62627	Tfpt	Rattus norvegicus	Q9JMG6	Pull Down	16229834
Cross	Pawr	Q62627	HSPA5	Homo sapiens	P11021	Pull Down	19632185
Intra	Pawr	Q62627	Dapk3	Rattus norvegicus	O88764	Protein Kinase Assay	10602480
Intra	Pawr	Q62627	Dapk3	Rattus norvegicus	O88764	IF	10602480
Intra	Pawr	Q62627	Dapk3	Rattus norvegicus	O88764	Y2H	10602480

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS10087	PAWR Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Pawr	NCBI	NCBI:5074

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