TSPYL5 - TSPY like 5 Gene

Homo sapiens

Gene ID: 85453 | Gene type: protein coding

About TSPYL5

Cytogenetic location: 8q22.1 Genomic coordinates (GRCh38): 8:97,273,488-97,277,928 (from NCBI)

This gene has 1 transcript (splice variant), 220 orthologues and 18 paralogues.

Summary

Predicted to enable chromatin binding activity and histone binding activity. Involved in several processes, including cellular response to gamma radiation; positive regulation of protein kinase B signaling; and positive regulation of protein ubiquitination. Predicted to be active in chromatin and nucleus. [provided by Alliance of Genome Resources, Apr 2022]

TSPYL5 Products(1)

mRNA	Protein	Name
NM_033512.3	NP_277047.2	testis-specific Y-encoded-like protein 5

Gene Ontology

Molecular Function
Biological Process

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	21170034	GOA

Biological Process GO Annotation	Evidence	Reference	Source
involved in cellular response to gamma radiation	IMP IMP: Inferred from mutant phenotype	20079711	GOA
involved in positive regulation of cell population proliferation	IDA IDA: Inferred from direct assay	21170034	GOA
involved in positive regulation of cell population proliferation	IMP IMP: Inferred from mutant phenotype	20079711	GOA
involved in positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction	IMP IMP: Inferred from mutant phenotype	20079711	GOA
involved in positive regulation of protein ubiquitination	IDA IDA: Inferred from direct assay	21170034	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

TSPYL5 Protein Structure

NAP

0
100
200
300
417 a.a.

Protein Preferred Names

Protein Names

testis-specific Y-encoded-like protein 5

TSPY-like protein 5

TSPYL5 Protein-protein interaction Information

Type Cross Intra	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Reference
Intra	TSPYL5	Q86VY4	USP7	Homo sapiens	Q93009	Anti Tag CoIP	21170034

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS15183	TSPYL5 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Felis catus	TSPYL5	VGNC	VGNC:81692
Mus musculus	TSPYL5	MGD	MGI:2442458
Canis familiaris	TSPYL5	VGNC	VGNC:54124
Macaca mulatta	TSPYL5	VGNC	VGNC:104504
Rattus norvegicus	TSPYL5	RGD	RGD:1311262

Name
Email *

	Sorry, but the email address you supplied was invalid.