RRP1 - ribosomal RNA processing 1 Gene

Homo sapiens

Also known as NNP-1; NOP52; RRP1A; D21S2056E

Gene ID: 8568 | Gene type: protein coding

About RRP1

Cytogenetic location: 21q22.3 Genomic coordinates (GRCh38): 21:43,789,577-43,805,293 (from NCBI)

This gene has 7 transcripts (splice variants), 195 orthologues and 1 paralogue. Ubiquitous expression in brain (RPKM 8.5), testis (RPKM 8.1) and 25 other tissues.

Summary

The protein encoded by this gene is the putative homolog of the yeast ribosomal RNA processing protein RRP1. The encoded protein is involved in the late stages of nucleologenesis at the end of mitosis, and may be required for the generation of 28S rRNA. [provided by RefSeq, Jul 2008]

RRP1 Products(1)

mRNA	Protein	Name
NM_003683.6	NP_003674.1	ribosomal RNA processing protein 1 homolog A

Gene Ontology

Molecular Function

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	20926688	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

RRP1 Protein Structure

Nop52

0
100
200
300
400
461 a.a.

Protein Preferred Names

Protein Names

ribosomal RNA processing protein 1 homolog A

Nnp1 homolog, nucleolar protein

Related Agents

Pre-clinical Phase

Bioactive Molecules (2)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS12289	RRP1 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS12291	RRP1B Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Bos taurus	RRP1	VGNC	VGNC:34168
Rattus norvegicus	RRP1	RGD	RGD:1307286
Mus musculus	RRP1	MGD	MGI:1203500
Felis catus	RRP1	VGNC	VGNC:64778
Canis familiaris	RRP1	VGNC	VGNC:45763
Macaca mulatta	RRP1	VGNC	VGNC:77050
Others	RRP1	NCBI

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