Prmt3 - protein arginine methyltransferase 3 Gene

Rattus norvegicus

Also known as Hrmt1l3

Gene ID: 89820 | Gene type: protein coding

About Prmt3

Primary_assembly 1: 99,492,724-99,579,435 forward strand.mRatBN7.2:CM026974.1

This gene has 2 transcripts (splice variants), 205 orthologues, 10 paralogues and is associated with 2 phenotypes. Biased expression in Muscle (RPKM 111.1), Spleen (RPKM 18.2) and 9 other tissues.

Summary

Enables modified amino acid binding activity and protein-arginine omega-N asymmetric methyltransferase activity. Involved in dendritic spine morphogenesis and peptidyl-arginine methylation, to asymmetrical-dimethyl arginine. Located in cytoplasm. Biomarker of asthma. Orthologous to human PRMT3 (protein arginine methyltransferase 3). [provided by Alliance of Genome Resources, Apr 2022]

Prmt3 Products(1)

mRNA	Protein	Name
NM_053557.1	NP_446009.1	protein arginine N-methyltransferase 3

Prmt3 Protein Structure

AdoMet_MTases

0
100
200
300
400
500
528 a.a.

Protein Preferred Names

Protein Names

protein arginine N-methyltransferase 3

heterogeneous nuclear ribonucleoprotein methyltransferase-like 3	heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 3
protein arginine N-methyltransferase 3(hnRNP methyltransferase S. cerevisiae)-like 3

Related Agents

Pre-clinical Phase

Bioactive Molecules (9)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-19615	MS023	Inhibitor	99.73%	Unkown
HY-19715	SGC707	Inhibitor	98.08%	Unkown
HY-19615B	MS023 dihydrochloride	Inhibitor	99.78%	Unkown
HY-128717B	GSK3368715 trihydrochloride	Inhibitor	/	Unkown
HY-161334	CARM1-IN-4	Inhibitor	/	Unkown
HY-159728	PROTAC PRMT3 degrader 1	Degrader	/	Unkown
HY-110158	UNC2327	Inhibitor	99.70%	Unkown
HY-146810	PRMT4-IN-1	Inhibitor	/	Unkown
HY-159732	PRMT3-IN-4	Inhibitor	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Prmt3	NCBI	NCBI:10196

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