2. Gene
  3. ADCK2 - aarF domain containing kinase 2 Gene

ADCK2 - aarF domain containing kinase 2 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as AARF

Gene ID: 90956 | Gene type: protein coding

About ADCK2

This gene has 5 transcripts (splice variants), 191 orthologues and 4 paralogues. Ubiquitous expression in skin (RPKM 8.8), brain (RPKM 7.6) and 25 other tissues.

Summary

Predicted to enable ATP binding activity and protein serine/threonine kinase activity. Predicted to be involved in protein phosphorylation. Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022]

ADCK2 Products(1)

mRNA Protein Name
NM_052853.4 NP_443085.2 uncharacterized aarF domain-containing protein kinase 2
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
27499296 GOA
Biological Process GO Annotation Evidence Reference Source
involved in regulation of ubiquinone biosynthetic process IDA
IDA: Inferred from direct assay
31480808 GOA
Cellular Component GO Annotation Evidence Reference Source
located in mitochondrion IDA
IDA: Inferred from direct assay
31480808 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

ADCK2 Protein Structure

ABC1

ABC1: ABC1 family (293 - 387)

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  • 500
  • 626 a.a.
Protein Preferred Names Protein Names

uncharacterized aarF domain-containing protein kinase 2

putative ubiquinone biosynthesis protein AarF

ADCK2 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Reference
Intra
ADCK2 Q7Z695 SLC25A5 Homo sapiens P05141
Anti Tag CoIP
27499296
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases Alias
Ovarian Melanoma
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS00324 ADCK2 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Felis catus ADCK2 VGNC VGNC:59611
Bos taurus ADCK2 VGNC VGNC:25640
Rattus norvegicus ADCK2 RGD RGD:1311058
Canis familiaris ADCK2 VGNC VGNC:37616
Mus musculus ADCK2 MGD MGI:1889336
Macaca mulatta ADCK2 VGNC VGNC:69473