2. Gene
  3. SYTL5 - synaptotagmin like 5 Gene

SYTL5 - synaptotagmin like 5 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens

Also known as slp5

Gene ID: 94122 | Gene type: protein coding

About SYTL5

This gene has 2 transcripts (splice variants), 206 orthologues and 31 paralogues. Broad expression in stomach (RPKM 4.3), placenta (RPKM 2.5) and 17 other tissues.

Summary

The protein encoded by this gene belongs to the synaptotagmin-like (Slp) protein family, which contains a unique homology domain at the N-terminus, referred to as the Slp homology domain (SHD). The SHD functions as a binding site for Rab27A, which plays a role in protein transport. Expression of this gene is restricted to placenta and liver, suggesting that it might be involved in Rab27A-dependent membrane trafficking in specific tissues. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]

SYTL5 Products(3)

mRNA Protein Name
NM_001163334.1 NP_001156806.1 synaptotagmin-like protein 5 isoform 2
NM_001163335.2 NP_001156807.1 synaptotagmin-like protein 5 isoform 1
NM_138780.3 NP_620135.1 synaptotagmin-like protein 5 isoform 1
Gene Ontology
  • Molecular Function
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
12051743 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

SYTL5 Protein Structure

FYVE_2

FYVE_2: FYVE-type zinc finger (13 - 123)

C2

C2: C2 domain (424 - 510)

C2

C2: C2 domain (589 - 677)

  • 0
  • 200
  • 400
  • 600
  • 730 a.a.
Protein Preferred Names Protein Names

synaptotagmin-like protein 5

exophilin 9

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS14126 SYTL5 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus SYTL5 RGD RGD:631342
Macaca mulatta SYTL5 VGNC VGNC:78125
Canis familiaris SYTL5 VGNC VGNC:47054
Bos taurus SYTL5 VGNC VGNC:35549
Mus musculus SYTL5 MGD MGI:2668451
Felis catus SYTL5 VGNC VGNC:65908