SEC16A - SEC16 homolog A, endoplasmic reticulum export factor Gene

Homo sapiens

Also known as p250; SEC16L; KIAA0310

Gene ID: 9919 | Gene type: protein coding

About SEC16A

Cytogenetic location: 9q34.3 Genomic coordinates (GRCh38): 9:136,440,105-136,484,740 (from NCBI)

This gene has 15 transcripts (splice variants), 191 orthologues and 1 paralogue. Ubiquitous expression in stomach (RPKM 11.7), bone marrow (RPKM 11.4) and 25 other tissues.

Summary

This gene encodes a protein that forms part of the Sec16 complex. This protein has a role in protein transport from the endoplasmic reticulum (ER) to the Golgi and mediates COPII vesicle formation at the transitional ER. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, Feb 2013]

SEC16A Products(2)

mRNA	Protein	Name
NM_001276418.2	NP_001263347.1	protein transport protein Sec16A isoform 2
NM_014866.2	NP_055681.1	protein transport protein Sec16A isoform 1

SEC16A Protein Structure

Sec16

Sec16_C

0
400
800
1200
1600
2000
2357 a.a.

Protein Preferred Names

Protein Names

protein transport protein Sec16A

protein SEC16 homolog A

Related Diseases

Diseases

Alias

Craniolenticulosutural Dysplasia

Boyadjiev-Jabs Syndrome	CLSD
Cranio-Lenticulo-Sutural Dysplasia	Cranio-Lenticulo-Sutural Dysplasia, Clsd

Mucinous Stomach Adenocarcinoma

Mucinous Adenocarcinoma Of The Stomach

Mucinous Gastric Adenocarcinoma

Amelogenesis Imperfecta, Type Iiia

Ai3	Adhcai
Amelogenesis Imperfecta Type 3	AI3A
Amelogenesis Imperfecta, Type Iii	Amelogenesis Imperfecta, Hypocalcification Type, Autosomal Dominant
Amelogenesis Imperfecta Type 3a	Amelogenesis Imperfecta Hypomineralization Type
Amelogenesis Imperfecta Type Iii	Hypocalcified Amelogenesis Imperfecta
Amelogenesis Imperfecta, Type 3	Amelogenesis Imperfecta, Hypomineralization Type
Autosomal Dominant Amelogenesis Imperfecta Hypocalcification Type	Amelogenesis Imperfecta 3a
Amelogenesis Imperfecta Hypocalcification Type Autosomal Dominant

Hereditary Spastic Paraplegia

Familial Spastic Paraplegia	Hereditary Spastic Paraparesis
Strumpell-Lorrain Disease	Familial Spastic Paraparesis
Hsp	Spg
Strümpell-Lorrain Disease	Spastic Paraplegia, Hereditary
French Settlement Disease	Strumpell-Lorrain Syndrome
Fsp	Spastic Paraplegia, Familial
Spastic Paraplegia Hereditary	Spastic Paraplegia 3, Autosomal Dominant
Spastic Paraparesis	Hereditary Spastic Paralysis
Familial Spastic Paralysis	Hereditary Spastic Ataxia

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS12609	SEC16A Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Felis catus	SEC16A	VGNC	VGNC:64963
Macaca mulatta	SEC16A	VGNC	VGNC:77326
Mus musculus	SEC16A	MGD	MGI:2139207
Canis familiaris	SEC16A	VGNC	VGNC:45965
Rattus norvegicus	SEC16A	RGD	RGD:2322350
Bos taurus	SEC16A	VGNC	VGNC:34406

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