2. Cell Cycle/DNA Damage PI3K/Akt/mTOR
  3. ATM/ATR
  4. GJ071 oxalate

GJ071 oxalate induces ATM kinase activity in ataxia telangiectasia (A-T) cells carrying homozygous TGA or TAG stop codons.

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GJ071 oxalate Chemical Structure

GJ071 oxalate Chemical Structure

CAS No. : 1216676-34-4

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Description

GJ071 oxalate induces ATM kinase activity in ataxia telangiectasia (A-T) cells carrying homozygous TGA or TAG stop codons[1].

Molecular Weight

455.53

Formula

C20H29N3O7S
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

S=C(N1CCN(CC2=CC=C(OCO3)C3=C2)CC1)NCCCOCC.O=C(O)C(O)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : 125 mg/mL (274.41 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.1952 mL 10.9762 mL 21.9525 mL
5 mM 0.4390 mL 2.1952 mL 4.3905 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.1952 mL 10.9762 mL 21.9525 mL 54.8811 mL
5 mM 0.4390 mL 2.1952 mL 4.3905 mL 10.9762 mL
10 mM 0.2195 mL 1.0976 mL 2.1952 mL 5.4881 mL
15 mM 0.1463 mL 0.7317 mL 1.4635 mL 3.6587 mL
20 mM 0.1098 mL 0.5488 mL 1.0976 mL 2.7441 mL
25 mM 0.0878 mL 0.4390 mL 0.8781 mL 2.1952 mL
30 mM 0.0732 mL 0.3659 mL 0.7317 mL 1.8294 mL
40 mM 0.0549 mL 0.2744 mL 0.5488 mL 1.3720 mL
50 mM 0.0439 mL 0.2195 mL 0.4390 mL 1.0976 mL
60 mM 0.0366 mL 0.1829 mL 0.3659 mL 0.9147 mL
80 mM 0.0274 mL 0.1372 mL 0.2744 mL 0.6860 mL
100 mM 0.0220 mL 0.1098 mL 0.2195 mL 0.5488 mL
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GJ071 oxalate Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

GJ0711216676-34-4GJ 071GJ-071ATM/ATRAtaxia telangiectasia mutatedATM and RAD3 relatedataxia telangiectasia,TGATAGstop codonsInhibitorinhibitorinhibit

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