2. Metabolic Enzyme/Protease Membrane Transporter/Ion Channel Autophagy
  3. CFTR Autophagy Potassium Channel P-glycoprotein Mitochondrial Metabolism
  4. Glibenclamide (Standard)

Glibenclamide (Standard)  (Synonyms: Glyburide (Standard))

Cat. No.: HY-15206R Purity: ≥98%
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Glibenclamide (Standard) is the analytical standard of Glibenclamide. This product is intended for research and analytical applications. Glibenclamide (Glyburide) is an orally active ATP-sensitive K+ channel (KATP) inhibitor and can be used for the research of diabetes and obesity. Glibenclamide inhibits P-glycoprotein. Glibenclamide directly binds and blocks the SUR1 subunits of KATP and inhibits the cystic fibrosis transmembrane conductance regulator protein (CFTR). Glibenclamide interferes with mitochondrial bioenergetics by inducing changes on membrane ion permeability. Glibenclamide can induce autophagy.

For research use only. We do not sell to patients.

Glibenclamide (Standard) Chemical Structure

Glibenclamide (Standard) Chemical Structure

CAS No. : 10238-21-8

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Glibenclamide (Standard) Related Classifications

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Glibenclamide (Standard)10238-21-8Glyburide (Standard)CFTRAutophagyPotassium ChannelP-glycoproteinMitochondrial MetabolismCystic fibrosis transmembrane conductance regulatorKcsAP-gpPgpMultidrug resistance protein 1MDR1ATP-binding cassette sub-family B member 1ABCB1Cluster of differentiation 243CD243ATP-sensitivediabetesobesitySUR1cysticfibrosistransmembraneconductanceregulatormitochondrialbioenergeticsautophagyadipocytesInhibitorinhibitorinhibit

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