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Glp-Asn-Pro-AMC is an inhibitor of thyrotropin-releasing hormone degrading enzyme (TRH-DE) with a Ki value of 0.97 μM.

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Glp-Asn-Pro-AMC Chemical Structure

Glp-Asn-Pro-AMC Chemical Structure

CAS No. : 291752-43-7

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50 mg USD 3800 In-stock
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Based on 1 publication(s) in Google Scholar

Glp-Asn-Pro-AMC Related Antibodies

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Description

Glp-Asn-Pro-AMC is an inhibitor of thyrotropin-releasing hormone degrading enzyme (TRH-DE) with a Ki value of 0.97 μM[1].

Molecular Weight

497.50

Formula

C24H27N5O7
CAS No.
Appearance

Solid

Sequence

{Glp}-Asn-Pro-{AMC}
Sequence Shortening

{Glp}-NP-{AMC}
SMILES

CC(C1=CC=C(NC([C@H]2N(CCC2)C([C@H](CC(N)=O)NC([C@@H]3CCC(N3)=O)=O)=O)=O)C=C1O4)=CC4=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : ≥ 125 mg/mL (251.26 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.0101 mL 10.0503 mL 20.1005 mL
5 mM 0.4020 mL 2.0101 mL 4.0201 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
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Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.0101 mL 10.0503 mL 20.1005 mL 50.2513 mL
5 mM 0.4020 mL 2.0101 mL 4.0201 mL 10.0503 mL
10 mM 0.2010 mL 1.0050 mL 2.0101 mL 5.0251 mL
15 mM 0.1340 mL 0.6700 mL 1.3400 mL 3.3501 mL
20 mM 0.1005 mL 0.5025 mL 1.0050 mL 2.5126 mL
25 mM 0.0804 mL 0.4020 mL 0.8040 mL 2.0101 mL
30 mM 0.0670 mL 0.3350 mL 0.6700 mL 1.6750 mL
40 mM 0.0503 mL 0.2513 mL 0.5025 mL 1.2563 mL
50 mM 0.0402 mL 0.2010 mL 0.4020 mL 1.0050 mL
60 mM 0.0335 mL 0.1675 mL 0.3350 mL 0.8375 mL
80 mM 0.0251 mL 0.1256 mL 0.2513 mL 0.6281 mL
100 mM 0.0201 mL 0.1005 mL 0.2010 mL 0.5025 mL
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Glp-Asn-Pro-AMC Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Glp-Asn-Pro-AMC291752-43-7OthersTRH-DEInhibitorpeptideinhibitorinhibit

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