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  4. GLUT4 activator 2

GLUT4 activator 2 (C59) is an insulin sensitizer, which can be used for research of diabetic diseases. GLUT4 activator 2 improves glucose uptake and insulin sensitivity in rodents. GLUT4 activator 2 interacts with Unc119 and Unc119B resulting in increased insulin sensitivity and GLUT4 translocation.

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GLUT4 activator 2 Chemical Structure

GLUT4 activator 2 Chemical Structure

CAS No. : 2761446-81-3

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10 mg USD 96 In-stock
25 mg USD 196 In-stock
50 mg USD 315 In-stock
100 mg USD 500 In-stock
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GLUT4 activator 2 Related Antibodies

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Description

GLUT4 activator 2 (C59) is an insulin sensitizer, which can be used for research of diabetic diseases. GLUT4 activator 2 improves glucose uptake and insulin sensitivity in rodents. GLUT4 activator 2 interacts with Unc119 and Unc119B resulting in increased insulin sensitivity and GLUT4 translocation[1].

Molecular Weight

325.23

Formula

C16H18Cl2N2O
CAS No.
Appearance

Solid

SMILES

O=C(C1(C[C@@H](C2)C3)C[C@@H]3C[C@@H]2C1)NC(N=C4)=CC(Cl)=C4Cl
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 125 mg/mL (384.34 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.0747 mL 15.3737 mL 30.7475 mL
5 mM 0.6149 mL 3.0747 mL 6.1495 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

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Volume (start)

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Concentration (final)

C2

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V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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(per animal)

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Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.0747 mL 15.3737 mL 30.7475 mL 76.8687 mL
5 mM 0.6149 mL 3.0747 mL 6.1495 mL 15.3737 mL
10 mM 0.3075 mL 1.5374 mL 3.0747 mL 7.6869 mL
15 mM 0.2050 mL 1.0249 mL 2.0498 mL 5.1246 mL
20 mM 0.1537 mL 0.7687 mL 1.5374 mL 3.8434 mL
25 mM 0.1230 mL 0.6149 mL 1.2299 mL 3.0747 mL
30 mM 0.1025 mL 0.5125 mL 1.0249 mL 2.5623 mL
40 mM 0.0769 mL 0.3843 mL 0.7687 mL 1.9217 mL
50 mM 0.0615 mL 0.3075 mL 0.6149 mL 1.5374 mL
60 mM 0.0512 mL 0.2562 mL 0.5125 mL 1.2811 mL
80 mM 0.0384 mL 0.1922 mL 0.3843 mL 0.9609 mL
100 mM 0.0307 mL 0.1537 mL 0.3075 mL 0.7687 mL
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GLUT4 activator 2 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

GLUT4 activator 22761446-81-3Othersinsulindiabetic diseasesInhibitorinhibitorinhibit

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