GLUT4 activator 2

Cat. No.: HY-164368: FAQs
Data Sheet Handling Instructions

Molarity Calculator

GLUT4 activator 2 (C59) is an insulin sensitizer, which can be used for research of diabetic diseases. GLUT4 activator 2 improves glucose uptake and insulin sensitivity in rodents. GLUT4 activator 2 interacts with Unc119 and Unc119B resulting in increased insulin sensitivity and GLUT4 translocation.

For research use only. We do not sell to patients.

GLUT4 activator 2 Chemical Structure

CAS No. : 2761446-81-3

Size	Price	Stock	Quantity
5 mg	USD 60	In-stock	Estimated Time of Arrival: December 31
10 mg	USD 96	In-stock	Estimated Time of Arrival: December 31
25 mg	USD 196	In-stock	Estimated Time of Arrival: December 31
50 mg	USD 315	In-stock	Estimated Time of Arrival: December 31
100 mg	USD 500	In-stock	Estimated Time of Arrival: December 31
200 mg		Get quote
500 mg		Get quote

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Customer Review

Based on 1 publication(s) in Google Scholar

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Purity & Documentation
References
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Description

Molecular Weight

325.23

Formula

C₁₆H₁₈Cl₂N₂O

CAS No.

2761446-81-3

Appearance

Solid

SMILES

O=C(C1(C[C@@H](C2)C3)C[C@@H]3C[C@@H]2C1)NC(N=C4)=CC(Cl)=C4Cl

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

DMSO : 125 mg/mL (384.34 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	3.0747 mL	15.3737 mL	30.7475 mL
5 mM	0.6149 mL	3.0747 mL	6.1495 mL
10 mM	0.3075 mL	1.5374 mL	3.0747 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Yin TC, et al. Insulin sensitization by small molecules enhancing GLUT4 translocation. Cell Chem Biol. 2023 Aug 17;30(8):933-942.e6. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	3.0747 mL	15.3737 mL	30.7475 mL	76.8687 mL
	5 mM	0.6149 mL	3.0747 mL	6.1495 mL	15.3737 mL
	10 mM	0.3075 mL	1.5374 mL	3.0747 mL	7.6869 mL
	15 mM	0.2050 mL	1.0249 mL	2.0498 mL	5.1246 mL
	20 mM	0.1537 mL	0.7687 mL	1.5374 mL	3.8434 mL
	25 mM	0.1230 mL	0.6149 mL	1.2299 mL	3.0747 mL
	30 mM	0.1025 mL	0.5125 mL	1.0249 mL	2.5623 mL
	40 mM	0.0769 mL	0.3843 mL	0.7687 mL	1.9217 mL
	50 mM	0.0615 mL	0.3075 mL	0.6149 mL	1.5374 mL
	60 mM	0.0512 mL	0.2562 mL	0.5125 mL	1.2811 mL
	80 mM	0.0384 mL	0.1922 mL	0.3843 mL	0.9609 mL
	100 mM	0.0307 mL	0.1537 mL	0.3075 mL	0.7687 mL