Glutarylcarnitine lithium

Name: Glutarylcarnitine lithium
Brand: MedChemExpress
SKU: HY-113005A
Rating: 4.5 (1 reviews)

Cat. No.: HY-113005A Purity: ≥99.0%: FAQs
Data Sheet SDS COA Handling Instructions

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Glutarylcarnitine lithium is the diagnostic metabolite for malonic aciduria and glutaric aciduria type I monitored in most tandem mass spectrometry newborn screening programmes.

For research use only. We do not sell to patients.

Glutarylcarnitine lithium Chemical Structure

Size	Price	Stock	Quantity
5 mg	USD 75	In-stock	Estimated Time of Arrival: December 31
10 mg	USD 120	In-stock	Estimated Time of Arrival: December 31
50 mg		Get quote
100 mg		Get quote

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Based on 1 publication(s) in Google Scholar

Other Forms of Glutarylcarnitine lithium:

Glutarylcarnitine Get quote

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Biological Activity
Purity & Documentation
References
Customer Review

Description

Glutarylcarnitine lithium is the diagnostic metabolite for malonic aciduria and glutaric aciduria type I monitored in most tandem mass spectrometry newborn screening programmes^[1].

IC₅₀ & Target

Human Endogenous Metabolite

In Vitro

Malonylcarnitine and Glutarylcarnitine are important diagnostic metabolites in the screening of dried blood spots by tandem mass spectrometry^[1].
The urinary excretion of glutarylcarnitine is a specific biochemical marker of glutaric acidemia type I (GA-1). The urinary excretion of glutarylcarnitine is an informative tool in the biochemical diagnosis of glutaric acidemia type I^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

281.23

Formula

C₁₂H₂₀LiNO₆

Appearance

Solid

Color

White to off-white

SMILES

C[N+](C)(C)C[C@H](OC(CCCC(O[Li])=O)=O)CC([O-])=O

Structure Classification

Ketones, Aldehydes, Acids

Initial Source

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility

In Vitro:

H₂O : ≥ 100 mg/mL (355.58 mM)

DMSO : 1 mg/mL (3.56 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	3.5558 mL	17.7790 mL	35.5581 mL
5 mM	0.7112 mL	3.5558 mL	7.1116 mL
10 mM	0.3556 mL	1.7779 mL	3.5558 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

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(per animal)

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(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

Purity & Documentation

Purity: ≥99.0%

Select Batch:

Data Sheet (270 KB) SDS (251 KB)

COA (247 KB)

Handling Instructions (2659 KB)

References

[1]. Johnson DW, et al. Stability of malonylcarnitine and Glutarylcarnitine in stored blood spots. J Inherit Metab Dis. 2004;27(6):789-90. [Content Brief]

[2]. S Tortorelli, et al. The urinary excretion of glutarylcarnitine is an informative tool in the biochemical diagnosis of glutaric acidemia type I. Mol Genet Metab. 2005 Feb;84(2):137-43. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO / H₂O	1 mM	3.5558 mL	17.7790 mL	35.5581 mL	88.8952 mL
H₂O	5 mM	0.7112 mL	3.5558 mL	7.1116 mL	17.7790 mL
	10 mM	0.3556 mL	1.7779 mL	3.5558 mL	8.8895 mL
	15 mM	0.2371 mL	1.1853 mL	2.3705 mL	5.9263 mL
	20 mM	0.1778 mL	0.8890 mL	1.7779 mL	4.4448 mL
	25 mM	0.1422 mL	0.7112 mL	1.4223 mL	3.5558 mL
	30 mM	0.1185 mL	0.5926 mL	1.1853 mL	2.9632 mL
	40 mM	0.0889 mL	0.4445 mL	0.8890 mL	2.2224 mL
	50 mM	0.0711 mL	0.3556 mL	0.7112 mL	1.7779 mL
	60 mM	0.0593 mL	0.2963 mL	0.5926 mL	1.4816 mL
	80 mM	0.0444 mL	0.2222 mL	0.4445 mL	1.1112 mL
	100 mM	0.0356 mL	0.1778 mL	0.3556 mL	0.8890 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.