Glutathione sulfonate (Synonyms: S-Sulfoglutathione)

Cat. No.: HY-167920 Purity: ≥95.0%: FAQs
Data Sheet SDS COA Handling Instructions Technical Support

Glutathione sulfonate (S-Sulfoglutathione) is a multifunctional bioactive compound that inhibits angiogenesis and tumor growth. Glutathione sulfonate is a competitive inhibitor of glutathione S-transferase and is involved in the detoxification process and the binding of a variety of exogenous and endogenous compounds. Glutathione sulfonate acts in the substrate binding site of Escherichia coli glutathione S-transferase, affecting the catalytic mechanism. The structural characteristics of Glutathione sulfonate contribute to its inhibitory effect by hydrogen bonding in the active center of the enzyme.

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Glutathione sulfonate Chemical Structure

CAS No. : 1637-70-3

Size	Stock	Quantity
5 mg	In-stock	Estimated Time of Arrival: December 31
10 mg	In-stock	Estimated Time of Arrival: December 31
50 mg	Get quote
100 mg	Get quote

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Description

Molecular Weight

387.39

Formula

C₁₀H₁₇N₃O₉S₂

CAS No.

1637-70-3

Appearance

Solid

Color

White to off-white

SMILES

OC([C@@H](N)CCC(N[C@@H](CSS(=O)(O)=O)C(NCC(O)=O)=O)=O)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

H₂O : 125 mg/mL (322.67 mM; Need ultrasonic)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	2.5814 mL	12.9069 mL	25.8138 mL
5 mM	0.5163 mL	2.5814 mL	5.1628 mL
10 mM	0.2581 mL	1.2907 mL	2.5814 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

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In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

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mg/kg

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

Purity & Documentation

Purity: ≥95.0%

Select Batch:

Data Sheet (269 KB) SDS (251 KB)

COA (247 KB) HNMR (251 KB)

Handling Instructions (2659 KB)

References

[1]. Three-dimensional structure of Escherichia coli glutathione S-transferase complexed with glutathione sulfonate: catalytic roles of Cys10 and His106

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

H₂O	1 mM	2.5814 mL	12.9069 mL	25.8138 mL	64.5344 mL
	5 mM	0.5163 mL	2.5814 mL	5.1628 mL	12.9069 mL
	10 mM	0.2581 mL	1.2907 mL	2.5814 mL	6.4534 mL
	15 mM	0.1721 mL	0.8605 mL	1.7209 mL	4.3023 mL
	20 mM	0.1291 mL	0.6453 mL	1.2907 mL	3.2267 mL
	25 mM	0.1033 mL	0.5163 mL	1.0326 mL	2.5814 mL
	30 mM	0.0860 mL	0.4302 mL	0.8605 mL	2.1511 mL
	40 mM	0.0645 mL	0.3227 mL	0.6453 mL	1.6134 mL
	50 mM	0.0516 mL	0.2581 mL	0.5163 mL	1.2907 mL
	60 mM	0.0430 mL	0.2151 mL	0.4302 mL	1.0756 mL
	80 mM	0.0323 mL	0.1613 mL	0.3227 mL	0.8067 mL
	100 mM	0.0258 mL	0.1291 mL	0.2581 mL	0.6453 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

Glutathione sulfonate Related Classifications

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Glutathione sulfonate1637-70-3S-SulfoglutathioneOthersInhibitorinhibitorinhibit

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Glutathione sulfonate (Synonyms: S-Sulfoglutathione)

Glutathione sulfonate Related Antibodies

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