GR 55562 hydrochloride

Name: GR 55562 hydrochloride
Brand: MedChemExpress
SKU: HY-W010869
Rating: 4.5 (1 reviews)

Cat. No.: HY-W010869: FAQs
Data Sheet Handling Instructions Technical Support

GR 55562 hydrochloride is a selective 5-HT_1B receptor antagonist. GR 55562 hydrochloride can be used for the research of nerve disease.

For research use only. We do not sell to patients.

GR 55562 hydrochloride Chemical Structure

CAS No. : 172854-55-6

Size	Stock	Quantity
5 mg	In-stock	Estimated Time of Arrival: December 31
10 mg	In-stock	Estimated Time of Arrival: December 31
50 mg	Get quote
100 mg	Get quote

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This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of GR 55562 hydrochloride:

GR 55562 dihydrochloride Get quote

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Biological Activity
Purity & Documentation
References
Customer Review

Description

GR 55562 hydrochloride is a selective 5-HT_1B receptor antagonist. GR 55562 hydrochloride can be used for the research of nerve disease^[1].

Molecular Weight

411.92

Formula

C₂₃H₂₆ClN₃O₂

CAS No.

172854-55-6

Appearance

Solid

Color

Light yellow to yellow

SMILES

O=C(NC1=CC=C(C2=CC=NC=C2)C=C1)C3=CC=C(O)C(CCCN(C)C)=C3.Cl

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

H₂O : ≥ 25 mg/mL (60.69 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	2.4277 mL	12.1383 mL	24.2766 mL
5 mM	0.4855 mL	2.4277 mL	4.8553 mL
10 mM	0.2428 mL	1.2138 mL	2.4277 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

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(per animal)

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(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Filip M, et al. Effects of serotonin (5-HT)(1B) receptor ligands, microinjected into accumbens subregions, on cocaine discrimination in rats. Naunyn Schmiedebergs Arch Pharmacol. 2002;366(3):226-234. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

H₂O	1 mM	2.4277 mL	12.1383 mL	24.2766 mL	60.6914 mL
	5 mM	0.4855 mL	2.4277 mL	4.8553 mL	12.1383 mL
	10 mM	0.2428 mL	1.2138 mL	2.4277 mL	6.0691 mL
	15 mM	0.1618 mL	0.8092 mL	1.6184 mL	4.0461 mL
	20 mM	0.1214 mL	0.6069 mL	1.2138 mL	3.0346 mL
	25 mM	0.0971 mL	0.4855 mL	0.9711 mL	2.4277 mL
	30 mM	0.0809 mL	0.4046 mL	0.8092 mL	2.0230 mL
	40 mM	0.0607 mL	0.3035 mL	0.6069 mL	1.5173 mL
	50 mM	0.0486 mL	0.2428 mL	0.4855 mL	1.2138 mL
	60 mM	0.0405 mL	0.2023 mL	0.4046 mL	1.0115 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.