Guanfacine-¹³C,d₅ hydrochloride

Cat. No.: HY-17416S2: FAQs
Data Sheet Handling Instructions

Molarity Calculator

Guanfacine-¹³C,d₅ hydrochloride is the deuterium and ¹³C labeled Guanfacine hydrochloride (HY-17416). Guanfacine hydrochloride is an orally active noradrenergic α2A agonist and has high selective for the α2A receptor subtype. Guanfacine has effects in producing hypotension and sedation. Guanfacine can be used for the research of a variety of prefrontal cortex (PFC) cognitive disorders, including tourette's syndrome and attention deficit hyperactivity disorder (ADHD).

For research use only. We do not sell to patients.

Guanfacine-<sup>13</sup>C,d<sub>5</sub> hydrochloride Chemical Structure

Guanfacine-¹³C,d₅ hydrochloride Chemical Structure

Size		Stock
1 mg		Get quote	Estimated Time of Arrival: December 31

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

Other Forms of Guanfacine-¹³C,d₅ hydrochloride:

Guanfacine hydrochloride In-stock

Featured Recommendations

•Related Small Molecules:

•Related Proteins:

View All Adrenergic Receptor Isoform Specific Products:

View All Isoforms

α adrenergic receptor β adrenergic receptor

Biological Activity
Purity & Documentation
References
Customer Review

Description	Guanfacine-¹³C,d₅ hydrochloride is the deuterium and ¹³C labeled Guanfacine hydrochloride (HY-17416). Guanfacine hydrochloride is an orally active noradrenergic α2A agonist and has high selective for the α2A receptor subtype. Guanfacine has effects in producing hypotension and sedation. Guanfacine can be used for the research of a variety of prefrontal cortex (PFC) cognitive disorders, including tourette's syndrome and attention deficit hyperactivity disorder (ADHD)^[1]^[2]^[3].
Molecular Weight	288.58
Formula	C₈¹³CH₅D₅Cl₃N₃O
Unlabeled CAS	29110-48-3
SMILES	O=C(N[13C](N)=N)C([2H])([2H])C1=C(Cl)C([2H])=C([2H])C([2H])=C1Cl.Cl
Shipping	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation	Data Sheet (271 KB) Handling Instructions (2659 KB)
References	[1]. Arnsten AF, et al. Guanfacine for the treatment of cognitive disorders: a century of discoveries at Yale. Yale J Biol Med. 2012 Mar;85(1):45-58. Epub 2012 Mar 29. [Content Brief] [2]. Van Zwieten PA, et al. The pharmacology of centrally acting antihypertensive drugs. Br J Clin Pharmacol. 1983;15(Suppl 4):455S–462S. [3]. Wang M, et al. Alpha2A-adrenoceptors strengthen working memory networks by inhibiting cAMP-HCN channel signaling in prefrontal cortex. Cell. 2007 Apr 20;129(2):397-410. [Content Brief]