Guanosine 5'-diphosphate-¹³C₁₀ dilithium (Synonyms: GDP-¹³C₁₀ dilithium)

Cat. No.: HY-113066S1: FAQs
Data Sheet Handling Instructions

Molarity Calculator

Guanosine 5'-diphosphate-¹³C₁₀ (GDP-¹³C₁₀) dilithium is ¹³C-labeled Guanosine 5'-diphosphate (HY-113066). Guanosine 5'-diphosphate (GDP) is a nucleoside diphosphate that activates adenosine 5'-triphosphate-sensitive K⁺ channel. Guanosine 5'-diphosphate is a potential iron mobilizer, which prevents the hepcidin-ferroportin interaction and modulates the interleukin-6 (IL-6)/stat-3 pathway. Guanosine 5'-diphosphate can be used in the research of inflammation, such as anemia of inflammation (AI).

For research use only. We do not sell to patients.

Guanosine 5'-diphosphate-<sup>13</sup>C<sub>10</sub> dilithium Chemical Structure

Guanosine 5'-diphosphate-¹³C₁₀ dilithium Chemical Structure

Size		Stock
1 mg		Get quote	Estimated Time of Arrival: December 31

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

Other Forms of Guanosine 5'-diphosphate-¹³C₁₀ dilithium:

Guanosine 5'-diphosphate disodium salt In-stock
Guanosine 5'-diphosphate Get quote
Guanosine 5'-diphosphate ditromethamine Get quote
Guanosine 5'-diphosphate (sodium), 96% (HPLC) Get quote
Guanosine 5'-diphosphate-¹⁵N₅ dilithium Get quote
Guanosine 5'-diphosphate-d¹³ dilithium Get quote
Guanosine 5'-diphosphate-¹³C₁₀,¹⁵N₅ dilithium Get quote

Featured Recommendations

•Related Small Molecules:

•Related Proteins:

Biological Activity
Purity & Documentation
References
Customer Review

Description	Guanosine 5'-diphosphate-¹³C₁₀ (GDP-¹³C₁₀) dilithium is ¹³C-labeled Guanosine 5'-diphosphate (HY-113066). Guanosine 5'-diphosphate (GDP) is a nucleoside diphosphate that activates adenosine 5'-triphosphate-sensitive K⁺ channel. Guanosine 5'-diphosphate is a potential iron mobilizer, which prevents the hepcidin-ferroportin interaction and modulates the interleukin-6 (IL-6)/stat-3 pathway. Guanosine 5'-diphosphate can be used in the research of inflammation, such as anemia of inflammation (AI).
In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1]. MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. Guanosine 5'-diphosphate-¹³C₁₀ dilithium Related Antibodies
Molecular Weight	461.97
Formula	¹³C₁₀H₁₀Li₂N₅O₁₁P₂
Unlabeled CAS	146-91-8
SMILES	O=P(OP(O[Li])(O[Li])=O)(O)O[13CH][13C@@H]1[13C@@](O)[13C@@](O)[13C@H](N2[13C](N=[13C](N)N[13C]3=O)=[13C]3N=[13CH]2)O1
Shipping	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation	Data Sheet (272 KB) Handling Instructions (2659 KB)
References	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief] [2]. S Kajioka, et al. Guanosine diphosphate activates an adenosine 5'-triphosphate-sensitive K+ channel in the rabbit portal vein. J Physiol. 1991 Dec;444:397-418. [Content Brief] [3]. Angmo S, et al. Identification of Guanosine 5'-diphosphate as Potential Iron Mobilizer: Preventing the Hepcidin-Ferroportin Interaction and Modulating the Interleukin-6/Stat-3 Pathway. Sci Rep. 2017 Jan 5;7:40097. [Content Brief]

Guanosine 5'-diphosphate-¹³C₁₀ dilithium Related Classifications

Inflammation/Immunology

Molarity Calculator
Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass		Concentration		Volume		Molecular Weight *
	=		×		×

The dilution calculator equation

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)	×	Volume _(start)	=	Concentration _(final)	×	Volume _(final)
	×		=		×
C1		V1		C2		V2

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Guanosine 5'-diphosphate-¹³C₁₀ dilithiumGDP-¹³C₁₀ dilithiumIsotope-Labeled CompoundsEndogenous MetabolitePotassium ChannelKcsAK+ channelIL-6/stat-3 pathwayhepcidininflammationanemiaAICaco-2HepG2Inhibitorinhibitorinhibit

Your Recently Viewed Products:

Product Name

Salutation

Applicant Name *

Email Address *

Phone Number *

Organization Name *

Department *

Requested quantity *

Country or Region *

Remarks

Product Name

Lot #

Applicant Name *

Email Address *

Phone Number

Department *

Organization Name *

Country or Region *

Remarks

Name
Email *

	Sorry, but the email address you supplied was invalid.

Guanosine 5'-diphosphate-13C10 dilithium (Synonyms: GDP-13C10 dilithium)

Other Forms of Guanosine 5'-diphosphate-13C10 dilithium:

Guanosine 5'-diphosphate-13C10 dilithium Related Antibodies

Featured Recommendations

•Related Small Molecules:

•Related Proteins:

Biological Activity

Purity & Documentation

References

Customer Review