Guanosine 5'-diphosphate ditromethamine (Synonyms: GDP ditromethamine)

Cat. No.: HY-113066B: FAQs
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Guanosine 5'-diphosphate ditromethamine is a nucleoside diphosphate that activates adenosine 5'-triphosphate-sensitive K⁺ channel. Guanosine 5'-diphosphate ditromethamine is a potential iron mobilizer, which prevents the hepcidin-ferroportin interaction and modulates the interleukin-6 (IL-6)/stat-3 pathway. Guanosine 5'-diphosphate ditromethamine can be used in the research of inflammation, such as anemia of inflammation (AI).

For research use only. We do not sell to patients.

Guanosine 5'-diphosphate ditromethamine Chemical Structure

CAS No. : 103192-39-8

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Other In-stock Forms of Guanosine 5'-diphosphate ditromethamine:

Guanosine 5'-diphosphate disodium salt

Other Forms of Guanosine 5'-diphosphate ditromethamine:

Guanosine 5'-diphosphate disodium salt In-stock
Guanosine 5'-diphosphate-¹⁵N₅ dilithium Get quote
Guanosine 5'-diphosphate-¹³C₁₀ dilithium Get quote
Guanosine 5'-diphosphate-d¹³ dilithium Get quote
Guanosine 5'-diphosphate-¹³C₁₀,¹⁵N₅ dilithium Get quote
Guanosine 5'-diphosphate Get quote
Guanosine 5'-diphosphate (sodium), 96% (HPLC) Get quote

2 Publications Citing Use of MCE Guanosine 5'-diphosphate ditromethamine

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Purity & Documentation
References
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Description

IC₅₀ & Target^[2]

Human Endogenous Metabolite

Molecular Weight

685.47

Formula

C₁₈H₃₇N₇O₁₇P₂

CAS No.

103192-39-8

SMILES

O=P(O)(OP(OC[C@@H]1[C@@H](O)[C@@H](O)[C@H](N2C=NC3=C2N=C(N)NC3=O)O1)(O)=O)O.OCC(CO)(N)CO.OCC(CO)(N)CO

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. S Kajioka, et al. Guanosine diphosphate activates an adenosine 5'-triphosphate-sensitive K+ channel in the rabbit portal vein. J Physiol. 1991 Dec;444:397-418. [Content Brief]

[2]. Angmo S, et al. Identification of Guanosine 5'-diphosphate as Potential Iron Mobilizer: Preventing the Hepcidin-Ferroportin Interaction and Modulating the Interleukin-6/Stat-3 Pathway. Sci Rep. 2017 Jan 5;7:40097. [Content Brief]

Guanosine 5'-diphosphate ditromethamine Related Classifications

Inflammation/Immunology

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass		Concentration		Volume		Molecular Weight *
	=		×		×

The dilution calculator equation

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)	×	Volume _(start)	=	Concentration _(final)	×	Volume _(final)
	×		=		×
C1		V1		C2		V2

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Guanosine 5'-diphosphate ditromethamine103192-39-8GDP ditromethaminePotassium ChannelEndogenous MetaboliteKcsAK+ channelIL-6/stat-3 pathwayhepcidininflammationanemiaAICaco-2HepG2Inhibitorinhibitorinhibit

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