H-N-Me-Ala-OH

Name: H-N-Me-Ala-OH
Brand: MedChemExpress
SKU: HY-W015926
Rating: 4.5 (1 reviews)

Cat. No.: HY-W015926 Purity: ≥96.0%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

H-N-Me-Ala-OH is an alanine derivative.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

H-N-Me-Ala-OH Chemical Structure

CAS No. : 3913-67-5

Size	Price	Stock	Quantity
10 g	USD 25	In-stock	Estimated Time of Arrival: December 31
25 g	USD 50	In-stock	Estimated Time of Arrival: December 31
50 g	USD 80	In-stock	Estimated Time of Arrival: December 31
100 g	USD 130	Get quote	Estimated Time of Arrival: December 31
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Based on 1 publication(s) in Google Scholar

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Description

H-N-Me-Ala-OH is an alanine derivative^[1].

In Vitro

Amino acids and amino acid derivatives have been commercially used as ergogenic supplements. They influence the secretion of anabolic hormones, supply of fuel during exercise, mental performance during stress related tasks and prevent exercise induced muscle damage. They are recognized to be beneficial as ergogenic dietary substances^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

103.12

Formula

C₄H₉NO₂

CAS No.

3913-67-5

Appearance

Solid

Color

White to off-white

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

DMSO : 25 mg/mL (242.44 mM; ultrasonic and adjust pH to 3 with HCl; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	9.6974 mL	48.4872 mL	96.9744 mL
5 mM	1.9395 mL	9.6974 mL	19.3949 mL
10 mM	0.9697 mL	4.8487 mL	9.6974 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo:

Select the appropriate dissolution method based on your experimental animal and administration route.

For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for in vivo experiments, it is recommended to prepare freshly and use it on the same day.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

Protocol 1

Add each solvent one by one: 10% DMSO 40% PEG300 5% Tween-80 45% Saline
Solubility: ≥ 2.5 mg/mL (24.24 mM); Clear solution

This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 400 μL PEG300, and mix evenly; then add 50 μL Tween-80 and mix evenly; then add 450 μL Saline to adjust the volume to 1 mL.
Preparation of Saline: Dissolve 0.9 g sodium chloride in ddH₂O and dilute to 100 mL to obtain a clear Saline solution.
Protocol 2

Add each solvent one by one: 10% DMSO 90% (20% SBE-β-CD in Saline)
Solubility: ≥ 2.5 mg/mL (24.24 mM); Clear solution

This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 900 μL 20% SBE-β-CD in Saline, and mix evenly.
Preparation of 20% SBE-β-CD in Saline (4°C, storage for one week): 2 g SBE-β-CD powder is dissolved in 10 mL Saline, completely dissolve until clear.
Protocol 3

Add each solvent one by one: 10% DMSO 90% Corn Oil
Solubility: ≥ 2.5 mg/mL (24.24 mM); Clear solution

This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown). If the continuous dosing period exceeds half a month, please choose this protocol carefully.
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 900 μL Corn oil, and mix evenly.

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Please enter your animal formula composition:

DMSO +

Tween-80 +

Saline

Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.

The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).

Calculation results:

Working solution concentration: mg/mL

Method for preparing stock solution: mg drug dissolved in μL DMSO (Stock solution concentration: mg/mL).

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only. If necessary, please contact MedChemExpress (MCE).

Method for preparing in vivo working solution for animal experiments: Take μL DMSO stock solution, add μL . μL , mix evenly, next add μL Tween 80, mix evenly, then add μL Saline.

If the continuous dosing period exceeds half a month, please choose this protocol carefully.

Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.

Purity & Documentation

Purity: 97.12%

Select Batch:

Data Sheet (271 KB) SDS (394 KB)

COA (247 KB) HNMR (113 KB) GC (184 KB) OR (83 KB)

Handling Instructions (2659 KB)

References

[1]. Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-1019. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	9.6974 mL	48.4872 mL	96.9744 mL	242.4360 mL
	5 mM	1.9395 mL	9.6974 mL	19.3949 mL	48.4872 mL
	10 mM	0.9697 mL	4.8487 mL	9.6974 mL	24.2436 mL
	15 mM	0.6465 mL	3.2325 mL	6.4650 mL	16.1624 mL
	20 mM	0.4849 mL	2.4244 mL	4.8487 mL	12.1218 mL
	25 mM	0.3879 mL	1.9395 mL	3.8790 mL	9.6974 mL
	30 mM	0.3232 mL	1.6162 mL	3.2325 mL	8.0812 mL
	40 mM	0.2424 mL	1.2122 mL	2.4244 mL	6.0609 mL
	50 mM	0.1939 mL	0.9697 mL	1.9395 mL	4.8487 mL
	60 mM	0.1616 mL	0.8081 mL	1.6162 mL	4.0406 mL
	80 mM	0.1212 mL	0.6061 mL	1.2122 mL	3.0304 mL
	100 mM	0.0970 mL	0.4849 mL	0.9697 mL	2.4244 mL

H-N-Me-Ala-OH Related Classifications

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Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

H-N-Me-Ala-OH3913-67-5Amino Acid DerivativesInhibitorinhibitorinhibit

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H-N-Me-Ala-OH

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Complete Stock Solution Preparation Table

H-N-Me-Ala-OH Related Classifications

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