1. Neuronal Signaling Stem Cell/Wnt PI3K/Akt/mTOR
  2. Cholinesterase (ChE) GSK-3
  3. hAChE/hBuChE/GSK-3β-IN-1

hAChE/hBuChE/GSK-3β-IN-1 (Compound 6c) is a BBB-penatrable and multi-target anti-Alzheimer's disease compound. hAChE/hBuChE/GSK-3β-IN-1 is the inhibitors of hAChE (IC50: 28.88 nM), hBuChE (IC50: 131.90 nM) and GSK-3β (IC50: 51.42 nM). hAChE/hBuChE/GSK-3β-IN-1 is the tau and protein aggregation inhibitors.

For research use only. We do not sell to patients.

hAChE/hBuChE/GSK-3β-IN-1 Chemical Structure

hAChE/hBuChE/GSK-3β-IN-1 Chemical Structure

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Description

hAChE/hBuChE/GSK-3β-IN-1 (Compound 6c) is a BBB-penatrable and multi-target anti-Alzheimer's disease compound. hAChE/hBuChE/GSK-3β-IN-1 is the inhibitors of hAChE (IC50: 28.88 nM), hBuChE (IC50: 131.90 nM) and GSK-3β (IC50: 51.42 nM). hAChE/hBuChE/GSK-3β-IN-1 is the tau and protein aggregation inhibitors[1].

IC50 & Target[1]

hAChE

28.88 nM (IC50)

hBCHE

131.90 nM (IC50)

GSK-3β

51.42 nM (IC50)

Molecular Weight

321.33

Formula

C19H15NO4

SMILES

O=C(/C=C/NC1=CC=C(OC(C=C2)=O)C2=C1)C3=CC=C(OC)C=C3

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
hAChE/hBuChE/GSK-3β-IN-1
Cat. No.:
HY-170417
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