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Halobetasol  (Synonyms: Ulobetasol)

Cat. No.: HY-113783 Purity: 99.10%
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Halobetasol (Ulobetasol) is a corticosteroid. Halobetasol can be used for research of severe localized psoriasis.

For research use only. We do not sell to patients.

Halobetasol Chemical Structure

Halobetasol Chemical Structure

CAS No. : 98651-66-2

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1 mg USD 50 In-stock
5 mg USD 125 In-stock
10 mg USD 200 In-stock
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This product is a controlled substance and not for sale in your territory.

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Based on 1 publication(s) in Google Scholar

Other Forms of Halobetasol:

Halobetasol Related Antibodies

Top Publications Citing Use of Products

  • Biological Activity

  • Purity & Documentation

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Description

Halobetasol (Ulobetasol) is a corticosteroid. Halobetasol can be used for research of severe localized psoriasis[1].

In Vitro

Halobetasol Related Antibodies

Cell Viability Assay[2]

Cell Line: HaCaT, THP-1
Concentration: 0.05-12.85 μM
Incubation Time: 24 h
Result: Affected decreasing the viability in both cell lines up to 50% corresponding to dilution 1/20.
In Vivo
Animal Model: New Zealand male albino rabbits[2]
Dosage: 0.5 ml
Administration: Intradermal injection
Result: Generated blisters were approximately 35% smaller.
Molecular Weight

428.90

Formula

C22H27ClF2O4
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

C[C@@]12[C@](O)([C@H](C[C@]1([C@@]3(C[C@@H](C4=CC(C=C[C@@]4([C@]3([C@H](C2)O)F)C)=O)F)[H])[H])C)C(CCl)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 250 mg/mL (582.89 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.3315 mL 11.6577 mL 23.3155 mL
5 mM 0.4663 mL 2.3315 mL 4.6631 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.3315 mL 11.6577 mL 23.3155 mL 58.2886 mL
5 mM 0.4663 mL 2.3315 mL 4.6631 mL 11.6577 mL
10 mM 0.2332 mL 1.1658 mL 2.3315 mL 5.8289 mL
15 mM 0.1554 mL 0.7772 mL 1.5544 mL 3.8859 mL
20 mM 0.1166 mL 0.5829 mL 1.1658 mL 2.9144 mL
25 mM 0.0933 mL 0.4663 mL 0.9326 mL 2.3315 mL
30 mM 0.0777 mL 0.3886 mL 0.7772 mL 1.9430 mL
40 mM 0.0583 mL 0.2914 mL 0.5829 mL 1.4572 mL
50 mM 0.0466 mL 0.2332 mL 0.4663 mL 1.1658 mL
60 mM 0.0389 mL 0.1943 mL 0.3886 mL 0.9715 mL
80 mM 0.0291 mL 0.1457 mL 0.2914 mL 0.7286 mL
100 mM 0.0233 mL 0.1166 mL 0.2332 mL 0.5829 mL
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Halobetasol Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Halobetasol98651-66-2UlobetasolOtherspsoriasiscorticosteroidInhibitorinhibitorinhibit

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