2. Cell Cycle/DNA Damage
  3. Haspin Kinase
  4. Haspin-IN-3

Haspin-IN-3 (compound 8l) is a potent haspin inhibitor with IC50 of 14 nM. Haspin-IN-3 has anticancer effects.

For research use only. We do not sell to patients.

Haspin-IN-3 Chemical Structure

Haspin-IN-3 Chemical Structure

CAS No. : 2416569-95-2

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1 mg USD 75 In-stock
5 mg USD 220 In-stock
10 mg USD 350 In-stock
50 mg USD 890 In-stock
100 mg USD 1230 In-stock
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Based on 1 publication(s) in Google Scholar

Haspin-IN-3 Related Antibodies

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Description

Haspin-IN-3 (compound 8l) is a potent haspin inhibitor with IC50 of 14 nM. Haspin-IN-3 has anticancer effects[1].

IC50 & Target

IC50: 14 nM (Haspin)[1]
Molecular Weight

278.26

Formula

C16H10N2O3
CAS No.
Appearance

Solid

Color

Light yellow to brown

SMILES

O=C1C2=C(O/C1=C\C3=CNC4=NC=CC=C34)C=C(C=C2)O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 25 mg/mL (89.84 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.5938 mL 17.9688 mL 35.9376 mL
5 mM 0.7188 mL 3.5938 mL 7.1875 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
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Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.5938 mL 17.9688 mL 35.9376 mL 89.8440 mL
5 mM 0.7188 mL 3.5938 mL 7.1875 mL 17.9688 mL
10 mM 0.3594 mL 1.7969 mL 3.5938 mL 8.9844 mL
15 mM 0.2396 mL 1.1979 mL 2.3958 mL 5.9896 mL
20 mM 0.1797 mL 0.8984 mL 1.7969 mL 4.4922 mL
25 mM 0.1438 mL 0.7188 mL 1.4375 mL 3.5938 mL
30 mM 0.1198 mL 0.5990 mL 1.1979 mL 2.9948 mL
40 mM 0.0898 mL 0.4492 mL 0.8984 mL 2.2461 mL
50 mM 0.0719 mL 0.3594 mL 0.7188 mL 1.7969 mL
60 mM 0.0599 mL 0.2995 mL 0.5990 mL 1.4974 mL
80 mM 0.0449 mL 0.2246 mL 0.4492 mL 1.1231 mL
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Haspin-IN-3 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Haspin-IN-32416569-95-2Haspin KinaseInhibitorinhibitorinhibit

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