His-Pro hydrochloride

Cat. No.: HY-111659A Purity: 99.84%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

His-Pro hydrochloride is a dipeptide consisting of histidyl and proline.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

His-Pro hydrochloride Chemical Structure

CAS No. : 2415727-78-3

Size	Price	Stock	Quantity
5 mg	USD 51	In-stock	Estimated Time of Arrival: December 31
10 mg	USD 80	In-stock	Estimated Time of Arrival: December 31
50 mg		Get quote
100 mg		Get quote

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This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of His-Pro hydrochloride:

His-Pro Get quote

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Biological Activity
Purity & Documentation
References
Customer Review

Description

His-Pro hydrochloride is a dipeptide consisting of histidyl and proline.

Molecular Weight

288.73

Formula

C₁₁H₁₇ClN₄O₃

CAS No.

2415727-78-3

Appearance

Solid

Color

White to off-white

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Sealed storage, away from moisture and light

Powder	-80°C	2 years
	-20°C	1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility

In Vitro:

DMSO : 125 mg/mL (432.93 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	3.4634 mL	17.3172 mL	34.6344 mL
5 mM	0.6927 mL	3.4634 mL	6.9269 mL
10 mM	0.3463 mL	1.7317 mL	3.4634 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

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mg/kg

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 99.84%

Select Batch:

Data Sheet (272 KB) SDS (252 KB)

COA (253 KB) HNMR (291 KB) LCMS (105 KB)

Handling Instructions (2659 KB)

References

[1]. Park SW, et al. Alterations in pancreatic protein expression in STZ-induced diabetic rats and genetically diabetic mice in response to treatment with hypoglycemic dipeptide Cyclo (His-Pro). Cell Physiol Biochem. 2012;29(3-4):603-16. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	3.4634 mL	17.3172 mL	34.6344 mL	86.5861 mL
	5 mM	0.6927 mL	3.4634 mL	6.9269 mL	17.3172 mL
	10 mM	0.3463 mL	1.7317 mL	3.4634 mL	8.6586 mL
	15 mM	0.2309 mL	1.1545 mL	2.3090 mL	5.7724 mL
	20 mM	0.1732 mL	0.8659 mL	1.7317 mL	4.3293 mL
	25 mM	0.1385 mL	0.6927 mL	1.3854 mL	3.4634 mL
	30 mM	0.1154 mL	0.5772 mL	1.1545 mL	2.8862 mL
	40 mM	0.0866 mL	0.4329 mL	0.8659 mL	2.1647 mL
	50 mM	0.0693 mL	0.3463 mL	0.6927 mL	1.7317 mL
	60 mM	0.0577 mL	0.2886 mL	0.5772 mL	1.4431 mL
	80 mM	0.0433 mL	0.2165 mL	0.4329 mL	1.0823 mL
	100 mM	0.0346 mL	0.1732 mL	0.3463 mL	0.8659 mL