1. Cell Cycle/DNA Damage Metabolic Enzyme/Protease GPCR/G Protein
  2. HSP Guanylate Cyclase
  3. Hsp110/sGC-modulator-1

Hsp110/sGC-modulator-1 (compound 17i), an orally active Hsp110/sGC dual-target regulator, exhibits optimal Hsp110 and sGC molecular activities as well as remarkable cell malignant phenotypes inhibitory and vasodilatory effects. Hsp110/sGC-modulator-1 (compound 17i) attenuates pulmonary vascular remodeling and right ventricular hypertrophy via Hsp110 suppression.

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Hsp110/sGC-modulator-1 Chemical Structure

Hsp110/sGC-modulator-1 Chemical Structure

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Description

Hsp110/sGC-modulator-1 (compound 17i), an orally active Hsp110/sGC dual-target regulator, exhibits optimal Hsp110 and sGC molecular activities as well as remarkable cell malignant phenotypes inhibitory and vasodilatory effects. Hsp110/sGC-modulator-1 (compound 17i) attenuates pulmonary vascular remodeling and right ventricular hypertrophy via Hsp110 suppression[1].

Molecular Weight

490.86

Formula

C24H18ClF3N2O4

Appearance

Solid

Color

White to off-white

SMILES

O=C(O)CCC1=CC=CC(NC(C2=CC(Cl)=CC=C2NC(C3=CC=C(C(F)(F)F)C=C3)=O)=O)=C1

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Purity & Documentation
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Hsp110/sGC-modulator-1
Cat. No.:
HY-159484
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