2. Membrane Transporter/Ion Channel
  3. Chloride Channel Sodium Channel
  4. Hydroflumethiazide

Hydroflumethiazide  (Synonyms: Methforylthiazidine; Rontyl)

Cat. No.: HY-W011240 Purity: 99.25%
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Hydroflumethiazide (Methforylthiazidine) is an orally active and potent thiazide diuretic. Hydroflumethiazide possesses the ability to directly stimulate A cell secretion in the normal and alloxan diabetic pancreas.

For research use only. We do not sell to patients.

Hydroflumethiazide Chemical Structure

Hydroflumethiazide Chemical Structure

CAS No. : 135-09-1

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Based on 1 publication(s) in Google Scholar

Other Forms of Hydroflumethiazide:

Hydroflumethiazide Related Antibodies

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  • Biological Activity

  • Purity & Documentation

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Description

Hydroflumethiazide (Methforylthiazidine) is an orally active and potent thiazide diuretic. Hydroflumethiazide possesses the ability to directly stimulate A cell secretion in the normal and alloxan diabetic pancreas[1][2][3].

Molecular Weight

331.30

Formula

C8H8F3N3O4S2
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=S(C1=C(C(F)(F)F)C=C(C2=C1)NCNS2(=O)=O)(N)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 125 mg/mL (377.30 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.0184 mL 15.0922 mL 30.1844 mL
5 mM 0.6037 mL 3.0184 mL 6.0369 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
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Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.0184 mL 15.0922 mL 30.1844 mL 75.4610 mL
5 mM 0.6037 mL 3.0184 mL 6.0369 mL 15.0922 mL
10 mM 0.3018 mL 1.5092 mL 3.0184 mL 7.5461 mL
15 mM 0.2012 mL 1.0061 mL 2.0123 mL 5.0307 mL
20 mM 0.1509 mL 0.7546 mL 1.5092 mL 3.7730 mL
25 mM 0.1207 mL 0.6037 mL 1.2074 mL 3.0184 mL
30 mM 0.1006 mL 0.5031 mL 1.0061 mL 2.5154 mL
40 mM 0.0755 mL 0.3773 mL 0.7546 mL 1.8865 mL
50 mM 0.0604 mL 0.3018 mL 0.6037 mL 1.5092 mL
60 mM 0.0503 mL 0.2515 mL 0.5031 mL 1.2577 mL
80 mM 0.0377 mL 0.1887 mL 0.3773 mL 0.9433 mL
100 mM 0.0302 mL 0.1509 mL 0.3018 mL 0.7546 mL
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Hydroflumethiazide Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Hydroflumethiazide135-09-1Methforylthiazidine RontylChloride ChannelSodium ChannelCl− Channels Na channelsNa+ channelsPhotosensitizerDiureticendocrine pancreasalloxan diabeticInhibitorinhibitorinhibit

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