2. Antibody-drug Conjugate/ADC Related PROTAC
  3. ADC Linker PROTAC Linkers
  4. Hydroxy-PEG3-(CH2)2-Boc

Hydroxy-PEG2-(CH2)2-Boc is a uncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Hydroxy-PEG2-(CH2)2-Boc is extracted from patent WO2004008101A2 (compound 196). Hydroxy-PEG2-(CH2)2-Boc is also a PROTAC linker that can be used in the synthesis of PROTACs.

For research use only. We do not sell to patients.

Hydroxy-PEG3-(CH2)2-Boc Chemical Structure

Hydroxy-PEG3-(CH2)2-Boc Chemical Structure

CAS No. : 186020-66-6

Size Price Stock Quantity
500 mg USD 45 In-stock
1 g USD 60 In-stock
5 g USD 200 In-stock
10 g USD 280 In-stock
25 g USD 550 In-stock
50 g   Get quote  

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 1 publication(s) in Google Scholar

Hydroxy-PEG3-(CH2)2-Boc Related Antibodies

Top Publications Citing Use of Products

View All ADC Linker Isoform Specific Products:

View All Isoforms
Cleavable Linker Non-cleavable Linker Acid Cleavable Linker Disulfide Cleavable Linker Protease Cleavable Linker Glycosidase Cleavable Linker Phosphatase Cleavable Linker

View All PROTAC Linkers Isoform Specific Products:

View All Isoforms
PEG Linkers Alkyl-Chain Linkers Alkyl/ether Linkers

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

Hydroxy-PEG2-(CH2)2-Boc is a uncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Hydroxy-PEG2-(CH2)2-Boc is extracted from patent WO2004008101A2 (compound 196)[1]. Hydroxy-PEG2-(CH2)2-Boc is also a PROTAC linker that can be used in the synthesis of PROTACs.

IC50 & Target

Non-cleavable Linker

 

PEGs

 

Alkyl/ether

 

In Vitro

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Hydroxy-PEG3-(CH2)2-Boc Related Antibodies
Molecular Weight

278.34

Formula

C13H26O6
CAS No.
Appearance

Liquid (Density: 1.052 g/cm3)

Color

Colorless to light yellow

SMILES

O=C(OC(C)(C)C)CCOCCOCCOCCO
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)

Purity & Documentation

Purity: ≥97.0%

SDS (393 KB)

COA (241 KB) HNMR (129 KB) LCMS (323 KB)

Handling Instructions (2659 KB)
References
  • No file chosen (Maximum size is: 1024 Kb)
  • If you have published this work, please enter the PubMed ID.
  • Your name will appear on the site.

Hydroxy-PEG3-(CH2)2-Boc Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Hydroxy-PEG3-(CH2)2-Boc186020-66-6ADC LinkerPROTAC LinkersAntibody-drug conjugates linkerADCLinkerWO2004008101A2Inhibitorinhibitorinhibit

Your Recently Viewed Products:

Inquiry Online

Your information is safe with us. * Required Fields.

Product Name

  

Salutation

Applicant Name *

 

Email Address *

Phone Number *

 

Organization Name *

Department *

 

Requested quantity *

Country or Region *

      

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
Hydroxy-PEG3-(CH2)2-Boc
Cat. No.:
HY-42488
Quantity:
MCE Japan Authorized Agent:

Customer Review

Thank You for Your Feedback!

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

Product Name

  

Lot #

Applicant Name *

 

Email Address *

Phone Number

 

Department *

Organization Name *

 

Country or Region *

Remarks

SAFETY DATA SHEET (SDS)

English - EN (393 KB) Français - FR (393 KB) Deutsch - DE (393 KB) Norwegian - NO (393 KB) Español - ES (393 KB) Swedish - SV (393 KB)

Request for HNMR Report

We have received your request and will respond to you as soon as possible.