2. Cell Cycle/DNA Damage
  3. Nucleoside Antimetabolite/Analog
  4. iBu-rG

iBu-rG  (Synonyms: N-Isobutyrylguanosine)

Cat. No.: HY-43057 Purity: ≥97.0%
COA Handling Instructions

Molarity Calculator

iBu-rG (N-Isobutyrylguanosine) is a nucleoside compound that can be used to synthesize oligoribonucleotides.

For research use only. We do not sell to patients.

iBu-rG Chemical Structure

iBu-rG Chemical Structure

CAS No. : 64350-24-9

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iBu-rG Related Antibodies

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Description

iBu-rG (N-Isobutyrylguanosine) is a nucleoside compound that can be used to synthesize oligoribonucleotides[1].

Molecular Weight

353.33

Formula

C14H19N5O6
CAS No.
Appearance

Solid

SMILES

O[C@H]1[C@@H](O)[C@H](N2C(N=C(NC(C(C)C)=O)NC3=O)=C3N=C2)O[C@@H]1CO
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : ≥ 100 mg/mL (283.02 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.8302 mL 14.1511 mL 28.3022 mL
5 mM 0.5660 mL 2.8302 mL 5.6604 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: 99.20%

COA (251 KB) HNMR (135 KB) RP-HPLC (200 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.8302 mL 14.1511 mL 28.3022 mL 70.7554 mL
5 mM 0.5660 mL 2.8302 mL 5.6604 mL 14.1511 mL
10 mM 0.2830 mL 1.4151 mL 2.8302 mL 7.0755 mL
15 mM 0.1887 mL 0.9434 mL 1.8868 mL 4.7170 mL
20 mM 0.1415 mL 0.7076 mL 1.4151 mL 3.5378 mL
25 mM 0.1132 mL 0.5660 mL 1.1321 mL 2.8302 mL
30 mM 0.0943 mL 0.4717 mL 0.9434 mL 2.3585 mL
40 mM 0.0708 mL 0.3538 mL 0.7076 mL 1.7689 mL
50 mM 0.0566 mL 0.2830 mL 0.5660 mL 1.4151 mL
60 mM 0.0472 mL 0.2359 mL 0.4717 mL 1.1793 mL
80 mM 0.0354 mL 0.1769 mL 0.3538 mL 0.8844 mL
100 mM 0.0283 mL 0.1415 mL 0.2830 mL 0.7076 mL
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iBu-rG Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

iBu-rG64350-24-9N-IsobutyrylguanosineNucleoside Antimetabolite/AnalognucleosideoligoribonucleotidesInhibitorinhibitorinhibit

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