iBu-rG (Synonyms: N-Isobutyrylguanosine)

Cat. No.: HY-43057 Purity: ≥97.0%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

iBu-rG (N-Isobutyrylguanosine) is a nucleoside compound that can be used to synthesize oligoribonucleotides.

For research use only. We do not sell to patients.

iBu-rG Chemical Structure

CAS No. : 64350-24-9

Size	Price	Stock	Quantity
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO ready for reconstitution	USD 55	In-stock	Estimated Time of Arrival: December 31
Solution
10 mM * 1 mL in DMSO	USD 55	In-stock	Estimated Time of Arrival: December 31
Solid
5 g	USD 50	Get quote	Estimated Time of Arrival: December 31
10 g	USD 80	Get quote	Estimated Time of Arrival: December 31
25 g	USD 160	Get quote	Estimated Time of Arrival: December 31
50 g		Get quote

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Description

iBu-rG (N-Isobutyrylguanosine) is a nucleoside compound that can be used to synthesize oligoribonucleotides^[1].

Molecular Weight

353.33

Formula

C₁₄H₁₉N₅O₆

CAS No.

64350-24-9

Appearance

Solid

Color

White to off-white

SMILES

O[C@H]1[C@@H](O)[C@H](N2C(N=C(NC(C(C)C)=O)NC3=O)=C3N=C2)O[C@@H]1CO

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

DMSO : ≥ 100 mg/mL (283.02 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	2.8302 mL	14.1511 mL	28.3022 mL
5 mM	0.5660 mL	2.8302 mL	5.6604 mL
10 mM	0.2830 mL	1.4151 mL	2.8302 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 99.20%

Select Batch:

Data Sheet (271 KB) SDS (393 KB)

COA (251 KB) HNMR (135 KB) RP-HPLC (200 KB)

Handling Instructions (2659 KB)

References

[1]. Eiko Ohtsuka, et al. Studies on tRNA and Related Compounds. XXXVII. Synthesis and Physical Properties of 2'- or 3'-O-(o-Nitrobenzyl) nucleosides : the Use of o-Nitrophenyldiazomethane as a Synthetic Reagent. Chemical & Pharmaceutical Bulletin, 29(2), 318–324.

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	2.8302 mL	14.1511 mL	28.3022 mL	70.7554 mL
	5 mM	0.5660 mL	2.8302 mL	5.6604 mL	14.1511 mL
	10 mM	0.2830 mL	1.4151 mL	2.8302 mL	7.0755 mL
	15 mM	0.1887 mL	0.9434 mL	1.8868 mL	4.7170 mL
	20 mM	0.1415 mL	0.7076 mL	1.4151 mL	3.5378 mL
	25 mM	0.1132 mL	0.5660 mL	1.1321 mL	2.8302 mL
	30 mM	0.0943 mL	0.4717 mL	0.9434 mL	2.3585 mL
	40 mM	0.0708 mL	0.3538 mL	0.7076 mL	1.7689 mL
	50 mM	0.0566 mL	0.2830 mL	0.5660 mL	1.4151 mL
	60 mM	0.0472 mL	0.2359 mL	0.4717 mL	1.1793 mL
	80 mM	0.0354 mL	0.1769 mL	0.3538 mL	0.8844 mL
	100 mM	0.0283 mL	0.1415 mL	0.2830 mL	0.7076 mL

iBu-rG Related Classifications

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Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

iBu-rG64350-24-9N-IsobutyrylguanosineNucleoside Antimetabolite/AnalognucleosideoligoribonucleotidesInhibitorinhibitorinhibit

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