Indole-3-acetamide-d₅

Name: Indole-3-acetamide-d 5
Brand: MedChemExpress
SKU: HY-W016784S
Rating: 4.5 (1 reviews)

Cat. No.: HY-W016784S Purity: 99.99%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

Indole-3-acetamide-d₅ is the deuterium labeled Indole-3-acetamide[1]. Indole-3-acetamide is a biosynthesis intermediate of indole-3-acetic acid (HY-18569). Indole-3-acetic acid is the most common natural plant growth hormone of the auxin class[2].

For research use only. We do not sell to patients.

Indole-3-acetamide-d<sub>5</sub> Chemical Structure

Indole-3-acetamide-d₅ Chemical Structure

CAS No. : 1204700-53-7

Size	Price	Stock	Quantity
1 mg	USD 70	In-stock	Estimated Time of Arrival: December 31
5 mg		Get quote
10 mg		Get quote

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Based on 1 publication(s) in Google Scholar

Other Forms of Indole-3-acetamide-d₅:

Indole-3-acetamide Get quote

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Biological Activity
Purity & Documentation
References
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Description

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

179.23

Formula

C₁₀H₅D₅N₂O

CAS No.

1204700-53-7

Unlabeled CAS

879-37-8

Appearance

Solid

Color

White to off-white

SMILES

[2H]C1=C([2H])C([2H])=C([2H])C2=C1NC([2H])=C2CC(N)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL (557.94 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

H₂O : 1.3 mg/mL (7.25 mM; Need ultrasonic)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	5.5794 mL	27.8971 mL	55.7942 mL
5 mM	1.1159 mL	5.5794 mL	11.1588 mL
10 mM	0.5579 mL	2.7897 mL	5.5794 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 99.99%

Select Batch:

Data Sheet (275 KB) SDS (251 KB)

COA (253 KB) HNMR (927 KB) RP-HPLC (893 KB)

Handling Instructions (2659 KB)

References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief]

[2]. Thomas Lehmann, et al. Indole-3-acetamide-dependent auxin biosynthesis: a widely distributed way of indole-3-acetic acid production? Eur J Cell Biol. 2010 Dec;89(12):895-905. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

H₂O / H₂O / DMSO / DMSO	1 mM	5.5794 mL	27.8971 mL	55.7942 mL	139.4856 mL
H₂O / H₂O / DMSO / DMSO	5 mM	1.1159 mL	5.5794 mL	11.1588 mL	27.8971 mL
DMSO / DMSO	10 mM	0.5579 mL	2.7897 mL	5.5794 mL	13.9486 mL
	15 mM	0.3720 mL	1.8598 mL	3.7196 mL	9.2990 mL
	20 mM	0.2790 mL	1.3949 mL	2.7897 mL	6.9743 mL
	25 mM	0.2232 mL	1.1159 mL	2.2318 mL	5.5794 mL
	30 mM	0.1860 mL	0.9299 mL	1.8598 mL	4.6495 mL
	40 mM	0.1395 mL	0.6974 mL	1.3949 mL	3.4871 mL
	50 mM	0.1116 mL	0.5579 mL	1.1159 mL	2.7897 mL
	60 mM	0.0930 mL	0.4650 mL	0.9299 mL	2.3248 mL
	80 mM	0.0697 mL	0.3487 mL	0.6974 mL	1.7436 mL
	100 mM	0.0558 mL	0.2790 mL	0.5579 mL	1.3949 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.