2. Immunology/Inflammation
  3. IRAK
  4. IRAK4-IN-10

IRAK4-IN-10 (compound 75) is a potent IRAK4 inhibitor with an IC50 of 1.5 nM. IRAK4-IN-10 blocks MyD88 dependent signaling. IRAK4-IN-9 has the potential for the research of inflammatory diseases, autoimmune diseases, and cancer.

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IRAK4-IN-10 Chemical Structure

IRAK4-IN-10 Chemical Structure

CAS No. : 2681278-09-9

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Description

IRAK4-IN-10 (compound 75) is a potent IRAK4 inhibitor with an IC50 of 1.5 nM. IRAK4-IN-10 blocks MyD88 dependent signaling. IRAK4-IN-9 has the potential for the research of inflammatory diseases, autoimmune diseases, and cancer[1].

IC50 & Target[1]

IRAK4

1.5 nM (IC50)

Molecular Weight

400.48

Formula

C22H24N8
CAS No.
SMILES

N#CC1=CC2=C(C=C1)C3=NC=C(C4=CN(C5CCNCC5)N=N4)C(NC(C)C)=C3N2
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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IRAK4-IN-10 Related Classifications

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Keywords:

IRAK4-IN-102681278-09-9IRAKInterleukin-1 receptor associated kinaseIL-1R associated kinaseMyD88toll-like receptorinflammatory diseasesautoimmune diseasescancerInhibitorinhibitorinhibit

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HY-143486
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