Isobutylamido thiazolyl resorcinol

Cat. No.: HY-W251181 Purity: 99.88%: FAQs
Data Sheet SDS COA Handling Instructions Technical Support

Isobutylamido thiazolyl resorcinol is a Tyrosinase inhibitor that can prevent UV-induced pigmentation.

For research use only. We do not sell to patients.

Isobutylamido thiazolyl resorcinol Chemical Structure

Size	Stock	Quantity
500 mg	In-stock	Estimated Time of Arrival: December 31
1 g	In-stock	Estimated Time of Arrival: December 31
5 g	Get quote	Estimated Time of Arrival: December 31
10 g	Get quote	Estimated Time of Arrival: December 31
25 g	Get quote	Estimated Time of Arrival: December 31
50 g	Get quote

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Purity & Documentation
References
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Description

Isobutylamido thiazolyl resorcinol is a Tyrosinase inhibitor that can prevent UV-induced pigmentation^[1]^[2].

Molecular Weight

278.33

Formula

C₁₃H₁₄N₂O₃S

CAS No.

1428450-95-6

Appearance

Solid

Color

White to off-white

SMILES

O=C(C(C)C)NC1=NC(C2=C(O)C=C(O)C=C2)=CS1

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)

Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL (359.29 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	3.5929 mL	17.9643 mL	35.9286 mL
5 mM	0.7186 mL	3.5929 mL	7.1857 mL
10 mM	0.3593 mL	1.7964 mL	3.5929 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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Working solution concentration: mg/mL

Purity & Documentation

Purity: 99.88%

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Data Sheet (268 KB) SDS (393 KB)

COA (247 KB) HNMR (121 KB) RP-HPLC (264 KB) LCMS (97 KB)

Handling Instructions (2659 KB)

References

[1]. Jin Li, et al. Recent advances in the design and discovery of synthetic tyrosinase inhibitors. Eur J Med Chem. 2021 Nov 15:224:113744. [Content Brief]

[2]. Vasanop Vachiramon, et al. Isobutylamido thiazolyl resorcinol for prevention of UVB-induced hyperpigmentation. J Cosmet Dermatol. 2021 Mar;20(3):987-992. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	3.5929 mL	17.9643 mL	35.9286 mL	89.8214 mL
	5 mM	0.7186 mL	3.5929 mL	7.1857 mL	17.9643 mL
	10 mM	0.3593 mL	1.7964 mL	3.5929 mL	8.9821 mL
	15 mM	0.2395 mL	1.1976 mL	2.3952 mL	5.9881 mL
	20 mM	0.1796 mL	0.8982 mL	1.7964 mL	4.4911 mL
	25 mM	0.1437 mL	0.7186 mL	1.4371 mL	3.5929 mL
	30 mM	0.1198 mL	0.5988 mL	1.1976 mL	2.9940 mL
	40 mM	0.0898 mL	0.4491 mL	0.8982 mL	2.2455 mL
	50 mM	0.0719 mL	0.3593 mL	0.7186 mL	1.7964 mL
	60 mM	0.0599 mL	0.2994 mL	0.5988 mL	1.4970 mL
	80 mM	0.0449 mL	0.2246 mL	0.4491 mL	1.1228 mL
	100 mM	0.0359 mL	0.1796 mL	0.3593 mL	0.8982 mL